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11 Jun 2017 - 15 Jun 2017
19 Jun 2017 - 22 Jun 2017


Image: A micrograph showing lipid nanoparticles (Photo courtesy of the University of the Basque Country).

Review Focuses on Lipid Nanoparticles as Gene Therapy Carriers

A recent review article focused on the potential of solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) for gene therapy, including the main advances in their application for the treatment of ocular diseases, infectious diseases, lysosomal storage disorders, and cancer and current research for their future clinical application. More...
01 Mar 2017
Image: A three-dimensional (3D) map of liver and pancreatic buds in a mouse embryo. Cells of the pancreas are marked in red and green, while liver cells appear in blue (Photo courtesy of Dr. Francesca Spagnoli, Max Delbrück Center for Molecular Medicine).

Reprogrammed Liver Cells Replace Nonfunctional Pancreatic Cells in Mouse Model

A team of cell biologists has developed a method for transforming liver cells into functioning, insulin-producing pancreatic cells and demonstrated its potential by treating diabetes in a mouse model. More...
28 Feb 2017
Image: Macrophages with ingested nanoparticles (green) (Photo courtesy of the Bourquin Laboratory, University of Geneva).

Assay Determines Suitability of Nanoparticles for In Vivo Use

A team of Swiss researchers has developed a flow cytometry-based test to determine whether specific types of nanoparticles are suitable for use in humans or animals. More...
28 Feb 2017
Image: A photomicrograph of a thyroid gland section: (1) follicles, (2) follicular cells, (3) endothelial cells (Photo courtesy of Wikimedia Commons).

Novel Method Enables Generation of Thyroid Tissue from Mouse Stem Cells

A novel method for generating thyroid cells (thyrocytes) from embryonic stem cells was demonstrated in a mouse model. More...
24 Feb 2017
Image: A laboratory-generated melanoma tumor (Photo courtesy of Dr. Aaron Smith, Queensland University of Technology).

Cancer Researchers Identify Factors That Drive Melanoma Metastasis

Cancer researchers have traced a molecular pathway that cycles melanoma cells between modes that favor growth of the primary tumor (progression) and modes that favor invasion of other parts of the body (metastasis). More...
23 Feb 2017
Image: Induced pluripotent stem cells (iPSCs) are the basis of a technique that opens the doors to many medical advances involving repair and restoration of tissues and organs (Photo courtesy of Darryl Leja, National Human Genome Research Institute).

Stem Cell Therapy is Safe: Reprogramming Does Not Increase the Rate of Mutagenesis

DNA mapping studies have shown that the genomes of induced pluripotent stem cells do not contain more mutations that did the original cell line from which they were generated. More...
22 Feb 2017
Image: A close-up image of a microfluidic chip used to fabricate nanoparticles that could be used to deliver therapeutic genes to specific organs of the body. Colored liquids have been added to highlight the channels (Photo courtesy of Rob Felt, Georgia Institute of Technology).

DNA Labels Simplify Development of Drug Delivery Nanoparticles

A team of biomedical engineers developed a method for labeling potential drug delivery nanoparticles with DNA "barcodes," which allowed the tracing of the nanoparticles within living test animals. More...
21 Feb 2017

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