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Events

12 Apr 2017 - 14 Apr 2017
22 Apr 2017 - 26 Apr 2017
New products on world’s medical product marketplace:

Therapeutics

Image: A model of an adeno-associated virus containing the DNA coding for the RNA guide, the Cas9 protein derived from Campylobacter jejuni, and the fluorescent reporter protein (GFP). This is possible because of the small size of Cas9 (Photo courtesy of the Institute for Basic Science).

Miniaturized Gene Editing for Treatment of Macular Regeneration

A viral vector was used to insert a very small CRISPR/Cas9 gene-editing tool into mouse muscle cells or retinal pigment epithelium cells, where it induced mutations that partially cured laser damage that mimicked human chronic age-related macular degeneration. More...
10 Mar 2017
Image: A new study has shown a link between idiopathic pulmonary fibrosis (IPF) and aging (Photo courtesy of Thinkstock).

Link Between Aging and Fibrotic Pulmonary Disease Discovered

A study analyzing transcriptome biomarker data has shown evidence linking cellular senescence with idiopathic pulmonary fibrosis (IPF), suggesting that this fatal lung disease maybe involve a form of accelerated aging. More...
09 Mar 2017
Image: A novel in vitro culture method enables disease fighting immune T-cells to overcome cancer\'s immunosuppressive effect (Photo courtesy of the Mayo Clinic).

Novel Culture Method for Activation of Cancer-Fighting T-Cells

A novel in vitro culture method enables disease fighting immune T-cells to overcome cancer's immunosuppressive effect in order to recognize and attack tumor cells upon being returned to the body. More...
02 Mar 2017
Image: A three-dimensional (3D) map of liver and pancreatic buds in a mouse embryo. Cells of the pancreas are marked in red and green, while liver cells appear in blue (Photo courtesy of Dr. Francesca Spagnoli, Max Delbrück Center for Molecular Medicine).

Reprogrammed Liver Cells Replace Nonfunctional Pancreatic Cells in Mouse Model

A team of cell biologists has developed a method for transforming liver cells into functioning, insulin-producing pancreatic cells and demonstrated its potential by treating diabetes in a mouse model. More...
28 Feb 2017
Image: Induced pluripotent stem cells (iPSCs) are the basis of a technique that opens the doors to many medical advances involving repair and restoration of tissues and organs (Photo courtesy of Darryl Leja, National Human Genome Research Institute).

Stem Cell Therapy is Safe: Reprogramming Does Not Increase the Rate of Mutagenesis

DNA mapping studies have shown that the genomes of induced pluripotent stem cells do not contain more mutations that did the original cell line from which they were generated. More...
22 Feb 2017
Image: An adult heart muscle cell, grown in a newborn rat heart (Photo courtesy of Chulan Kwon, Johns Hopkins University School of Medicine).

Mature Heart Muscle Cells Created from Implanted Stem Cells

Bypassing a longstanding tissue culture challenge, researchers have succeeded in generating mature and viable human heart muscle cells in the laboratory by implanting, into newborn rat hearts, induced pluripotent stem cells (I-PSCs) from a healthy adult or an adult with a type of heart disease. The host rat heart provides the signals and chemistry needed by the implanted human immature heart muscle cells to progress and overcome the developmental block that has otherwise prevented their maturation in lab cultures. More...
10 Feb 2017
Image: A photomicrograph showing numerous immune suppressive cells in green and yellow, infiltrating the tumor mass (tumor cells in white). By depleting these immune suppressive cells, immunotherapy becomes much more effective (Photo courtesy of the University of Michigan).

Combined Gene and Immunotherapy Shows Potential for Aggressive Brain Tumors

A novel approach that combined gene and immunotherapy demonstrated considerable potential in a mouse model as a method for treating the aggressive brain tumor glioblastoma multiforme (GBM). More...
17 Jan 2017

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BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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