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Genomics/Proteomics

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Image: The TheraCyte cell encapsulation device (Photo courtesy of TheraCyte, Inc.).

Encapsulated Human-Insulin-Producing Progenitor Cells Cure Diabetes in Mouse Model

A breakthrough system that allows subcutaneous implantation of encapsulated immature pancreatic cells (beta progenitor cells) was shown to produce enough insulin to correct the symptoms of diabetes in a mouse model.... Read more

Drug Discovery

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Image: Chitosan is derived from the shells of shrimp and other sea crustaceans, including Alaskan pink shrimp, pictured here (Photo courtesy of NOAA - [US] National Oceanic and Atmospheric Administration).

Chitosan Treatment Clears the Way for Antibiotics to Eliminate Recurrent Urinary Tract Infections

Recurrent urinary tract infection was successfully resolved in a mouse model by treatment with the exfoliant chitosan followed by a round of antibiotics. Bacterial urinary tract infection (UTI), most... Read more

Biochemistry

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Mitochondrial Cause of Aging Can Be Reversed

Researchers have found a cause of aging in lab animals that can be reversed, possibly providing an avenue for new treatments for age-related diseases including type 2 diabetes, cancer, muscle wasting, and inflammatory diseases. The researchers plan to begin human trials late 2014. The study, which was published December... Read more

Therapeutics

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Cytokine Identified That Causes Mucositis in Cancer Therapy Patients

The action of the cytokine interleukin 1-beta (IL-1beta) has been found to underlie the onset of mucositis, a common, severe side effect of chemotherapy and irradiation of cancer patients. Mucositis occurs as a result of cell death in reaction to chemo- or radiotherapy. The mucosal lining of the mouth becomes thin, may... Read more

Lab Technologies

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Image: Co-evolved mutations in genetic sequences that code proteins show researchers how a protein is likely to fold and what forms it may take as it carries out its function. Scientists from Rice University used the technique called direct coupling analysis in combination with structure-based models to find a previously hidden conformation of a molecular motor responsible for degrading misfolded proteins in bacteria (Photo courtesy of Faruck Morcos/Rice University).

Big Data’s Direct Coupling Analysis Reveals Clues About Molecular Protease Machines

Researchers have merged genetic and structural data in a Big Data attempt to solve one of the most fascinating mysteries in biology: how proteins perform the regulatory processes in cells upon which all... Read more

Business

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Sonrgy in Licensing Agreement with UC San Diego for Drug Delivery Nanotech

Sonrgy, Inc. (San Diego, CA, USA), a biotechnology company developing focused drug delivery technologies, has obtained an exclusive license agreement with the University of California (UC; USA) for the company’s core technology, an ultrasound-sensitive drug delivery platform. The agreement gives the company the sole... Read more
 
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