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Genomics/Proteomics

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Image: Ball-and-stick model of the naphthalene molecule, as determined from X-ray crystallographic data (Photo courtesy of Wikimedia Commons).

Naphthalene-Dipeptide Hydrogels Destroy Antibiotic-Resistant Bacterial Biofilms

Novel hydrogels derived from self-assembling dipeptides conjugated to naphthalene were shown to dissolve bacterial biofilms, which indicated considerable promise for use in constructing bacteria-resistant... Read more

Drug Discovery

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Image: (Left) Neurons in brains from people with autism do not undergo normal pruning during childhood and adolescence. The images show representative neurons from unaffected brains (left) and brains from autistic patients (right); the spines on the neurons indicate the location of synapses (Photo courtesy of Guomei Tang, PhD and Mark S. Sonders, PhD, Columbia University Medical Center).

Autistic Youngsters Found to Have Too Many Brain Synapses

Autistic children and adolescents have been shown to have an excess of brain synapses, and this is due to a slowdown in the normal brain “trimming” process during development, according to new findings.... Read more

Therapeutics

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Image: Liver cells regenerated in mice treated with a new drug (right) compared with a control group (center) after partial liver removal. Healthy liver cells are shown at left (Photo courtesy of Marshall et al, 2014, the Journal of Experimental Medicine).

New Drug Triggers Liver Regeneration After Surgery

Investigators have revealed that an innovative complement inhibitor decreases complement-mediated liver cell death, and actually stimulates postsurgery liver regrowth in mice. Liver cancer often results... Read more

Lab Technologies

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Image: Co-Lead author of the study, Livia Eberlin, PhD, operating a DESI-MS system (Photo courtesy of Purdue News Service).

Desorption Electrospray Ionization Mass Spectrometry Imaging Guides Removal of Brain Tumors

US researchers have developed an imaging system that rapidly and accurately detects a molecular marker found in brain gliomas. The technology has the potential to optimize the precision of these difficult... Read more

Business

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Theraclone Partners with Gilead Sciences for Neutralizing HIV Antibody Technology

Theraclone Sciences, Inc. (Seattle, WA, USA), a therapeutic antibody discovery and development company, has entered into an agreement with Gilead Sciences, Inc. (Foster City, CA, USA), under which Gilead received an exclusive license to develop and commercialize products integrating Theraclone’s broadly neutralizing HIV-antibodies... Read more
 
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