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Image: This fMRI scan shows the brain area outlined in yellow is the hippocampus; the dentate gyrus is shown in green and the entorhinal cortex in purple. Previous work, including by the laboratory of senior author Scott A. Small, M.D., had shown that changes in a specific part of the brain’s hippocampus--the dentate gyrus--are associated with normal age-related memory decline in humans and other mammals. The dentate gyrus is distinct from the entorhinal cortex, the hippocampal region affected in early-stage Alzheimer’s disease (Photo courtesy of the Laboratory of Scott A. Small, MD).

Mapping Tool Reveals Cocoa May Reverse Age-Related Memory Decline

Dietary cocoa flavanols, naturally occurring bioactives found in cocoa, has been shown to reverse age-related memory decline in healthy older adults, according to new findings. Flavanols are also found naturally in tea leaves and in specific fruits and vegetables.  More...
05 Nov 2014
Image: (A) Biodegradable polymeric nanoparticles. (B) Test to analyze short-term memory in transgenic mice with Alzheimer. (C and D) Markers to analyze neurogenesis (Photo courtesy of the University of the Basque Country).

Micro-, Nano-particles Designed to Enhance Treatments for Alzheimer’s and Parkinson’s

Techniques are being developed to effectively deliver specific drugs to treat Alzheimer’s and Parkinson’s disease.   More...
29 Oct 2014
SLAS - Society for Laboratory Automation and Screening

Boosting the Heart’s Natural Capacity to Recuperate After Heart Attack with Key Protein

By increasing up the levels of a well-known protein in the heart, researchers have discovered a new way to generate more blood vessels following a heart attack.   More...
27 Oct 2014
Image: Biomaterials were designed to specifically accommodate cardiac, neuronal, and stem cells. The biomaterials temporarily replace the native ECM, providing support and instructive cues to the developing tissues. Post implantation the biomaterial degrades leaving the engineered tissue to stand on its own (Photo courtesy of Tel Aviv University).

Gold Nanoparticles Improve Cellular Signaling in Novel Heart Repair Tissue

An Israeli research team has developed a novel gold nanoparticle-based approach for repairing damaged heart tissue.  More...
09 Oct 2014

MRI Technology Enables Noninvasive Monitoring of Emergent Cell Therapies

Cellular therapeutics, the application of using intact cells to treat and cure disease, is an important potential new therapeutic application, but it is hampered by the inability of clinicians and scientists to effectively monitor the destination, movements, and perseverance of these cells in patients without having to use invasive procedures, such as tissue sampling.   More...
07 Oct 2014

MRI Technology Designed for Diagnosing Painful Back Disorder

A new imaging technique used to identify biomarkers could indicate which patients have a painful, degenerative back condition is under development.  More...
06 Oct 2014
Image: Aggressor cells, which have the potential to cause autoimmunity, are targeted by treatment, causing conversion of these cells to protector cells. Gene expression changes gradually at each stage of treatment, as illustrated by the color changes in this series of heat maps (Photo courtesy of the University of Bristol/Dr. Bronwen Burton).

“Switch Off Button” Discovered in Autoimmune Disorders

Scientists have made an important advance in the fight against debilitating autoimmune diseases such as multiple sclerosis by demonstrating how to stop cells destroy healthy body tissue. Instead of the body’s immune system destroying its own tissue by mistake, researchers have discovered how cells can be transformed from being aggressive to actually protecting against disease.  More...
22 Sep 2014

BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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