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Therapeutics

Image: New lung cells are continuously created to replace the damaged ones: Lung tissue six weeks after stem cell transplantation (left) and 16 weeks after transplantation (right). Cells that originated in the transplanted stem cells are green, as opposed to the uncolored host lung cells (Photo courtesy of the Weizmann Institute of Science).

Bone Marrow Transplantation Techniques Are Successfully Adapted for Lung Repair

A new approach for repairing the damage caused to lung tissue by diseases such as emphysema, bronchitis, asthma, and cystic fibrosis is based on transplanting embryonic stem cells into damaged lungs that have been conditioned by radiation treatment.  More...
29 Jul 2015
Image: Using a transmission electron microscope (TEM): (A) a bare nanoparticle, (B) a nanoparticle prepared for coating and (C) a nanoparticle coated with a thin layer of drug-delivering hydrogels (Photo courtesy of Dr. Jennifer West, Duke University).

Drug Augmented, Light-Activated Nanoparticles Effectively Kill Cancer Cells

The inclusion of a chemotherapeutic agent within a novel class of light-sensitive nanoparticles enhanced their ability to kill cancer cells.  More...
28 Jul 2015

Promising Cancer Immunotherapy Method Relies on Artificial Magnetic Antigen Presenting Cells

Cancer researchers have developed a method based on magnetic nanoparticles that enables the rapid extraction, enrichment, and expansion of a T-cell population that shows great promise as a tool for immunotherapy.  More...
26 Jul 2015

Swimming Nanorobots Could Provide Targeted Drug Delivery

Nano-sized swimmer robots that move in an S-like, undulatory motion could move easily through body fluids to deliver drugs to their targets.  More...
15 Jul 2015

Highly Elastic Protein Gel Encourages Wound Healing

A new study describes a protein-based gel that mimics many of the properties of elastic tissue—such as skin and blood vessels—when exposed to light.  More...
15 Jul 2015
Image: Photograph (left) and optical microscopic (right) images of the new hydrogels with polyethylene glycol (PEG) microstructures developed to enable burst-free sustained-release of PEGylated protein drugs such as PEGylated interferon (Photo courtesy of A*STAR’s Institute of Bioengineering and Nanotechnology).

New Gel Extends Release Half-Life of PEGylated Drugs

Researchers have developed a first-of-its-kind hydrogel for more effective long-term drug delivery that would also reduce side-effects and discomfort for patients. Their proof-of-concept study showed effectiveness of the hydrogel with the hepatitis C drug PEGylated-interferon.  More...
08 Jul 2015
Image: A photmicrograph of medium spiny neurons (yellow) with nuclear inclusions (orange), which occur as part of the Huntington\'s disease process. Several neurons are colored yellow and have a large central core with up to two dozen tendrils branching out of them. The core of the neuron in the foreground contains an orange blob about a quarter of its diameter (Photo courtesy of Wikimedia Commons).

Seeding Assay May Boost Search for Huntington's Disease Drugs

An assay technique that measures seeding of mutant huntingtin aggregates in cerebral spinal fluid may identify individuals with Huntington's disease that have not yet become symptomatic and may be used to evaluate the efficacy of new drug treatments for the disease.  More...
07 Jul 2015


BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
 
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