Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Events

05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017

Pilot Projects Initiated to Create Cancer Genomics Cloud

By BiotechDaily International staff writers
Posted on 03 Feb 2014
ADVERTISEMENT
SARTORIUS AG
The US National Cancer Institute (NCI; Rockville, MD, USA) has allotted USD 20 million for cloud-based genomics pilot projects, realizing that it is faced with rising data struggles. Because the scale of its projects increases—one initiative is expected to generate 2.5 petabytes of data—downloading analysis findings on local systems becomes unrealistic.

The NCI is now seeking organizations that can help in its goals, having spent 2013 collecting on user feedback oh what they need from cloud-based cancer genomics. The plan is to promote the development of multiple pilot projects that will undergo a competitive assessment. The NCI, after consulting with cancer researchers, will select one or more of the projects, or a modification of them, as the production version. Finally, the project will be sourced into a Cancer Knowledge Commons that aggregates all data.

The last phase of the project is to optimize NCI-generated data access by decreasing the technical requirements for researchers. Data are downloaded, in the current system, for analysis with locally developed and run tools. The dependence on local systems translates into organizations without top-tier computing power and capabilities can do less with the data. Correspondingly, storing petabytes of data is impractical for some groups. With data pools growing quickly, storage costs will also increase.

The NCI views cloud-based genomics systems will serve as the solution. Storing data and running analysis tools in the cloud will lessen the computing power needed for end users to search for clues in the results. Even prominent research institutions should benefit from using a cloud-based system, as data download times are on the cusp of becoming impractical. Using a point-to-point 10-gigabit network, downloading the 2.5 petabytes generated by the Cancer Genome Atlas would take weeks.

The NCI’s new initiative will be, as aforementioned, the first step toward the establishment of a full Cancer Knowledge Commons, relative to the US National Academy report on Precision Medicine, and will be coordinated with the National Institutes of Health’s (Bethesda, MD, USA) Big Data to Knowledge (BD2K) initiative and other pertinent activities in large-scale data analysis.

Related Links:

US National Cancer Institute



Channels

Drug Discovery

view channel
Image: The experimental drug NGI-1 slows cancer growth by blocking glycosylation of the epidermal growth factor receptor (EGFR), which is shown in the above diagram (Photo courtesy of Wikimedia Commons).

Experimental Drug Slows Lung Cancer Growth by Blocking Protein Glycosylation

An interesting new experimental anti-cancer drug slows growth of certain lung tumor cells by preventing the glycosylation of critical cell surface receptor proteins. Asparagine (N)-linked glycosylation... Read more

Biochemistry

view channel
Image: A space-filling model of the anticonvulsant drug carbamazepine (Photo courtesy of Wikimedia Commons).

Wastewater May Contaminate Crops with Potentially Dangerous Pharmaceuticals

Reclaimed wastewater used to irrigate crops is contaminated with pharmaceutical residues that can be detected in the urine of those who consumed such produce. Investigators at the Hebrew University... Read more

Business

view channel

Collaborative Agreement to Aid in Setting Guidelines for Evaluating Potential Ebola Therapy

Cooperation between an Israeli biopharmaceutical company and medical branches of the US government is designed to set ground rules for continued evaluation of an experimental therapy for Ebola virus disease. RedHill Biopharma Ltd. (Tel Aviv, Israel), a biopharmaceutical company primarily focused on development and c... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.