Features | Partner Sites | Information | LinkXpress
Sign In
PZ HTL SA
GLOBETECH PUBLISHING
GLOBETECH PUBLISHING

Pilot Projects Initiated to Create Cancer Genomics Cloud

By BiotechDaily International staff writers
Posted on 03 Feb 2014
The US National Cancer Institute (NCI; Rockville, MD, USA) has allotted USD 20 million for cloud-based genomics pilot projects, realizing that it is faced with rising data struggles. Because the scale of its projects increases—one initiative is expected to generate 2.5 petabytes of data—downloading analysis findings on local systems becomes unrealistic.

The NCI is now seeking organizations that can help in its goals, having spent 2013 collecting on user feedback oh what they need from cloud-based cancer genomics. The plan is to promote the development of multiple pilot projects that will undergo a competitive assessment. The NCI, after consulting with cancer researchers, will select one or more of the projects, or a modification of them, as the production version. Finally, the project will be sourced into a Cancer Knowledge Commons that aggregates all data.

The last phase of the project is to optimize NCI-generated data access by decreasing the technical requirements for researchers. Data are downloaded, in the current system, for analysis with locally developed and run tools. The dependence on local systems translates into organizations without top-tier computing power and capabilities can do less with the data. Correspondingly, storing petabytes of data is impractical for some groups. With data pools growing quickly, storage costs will also increase.

The NCI views cloud-based genomics systems will serve as the solution. Storing data and running analysis tools in the cloud will lessen the computing power needed for end users to search for clues in the results. Even prominent research institutions should benefit from using a cloud-based system, as data download times are on the cusp of becoming impractical. Using a point-to-point 10-gigabit network, downloading the 2.5 petabytes generated by the Cancer Genome Atlas would take weeks.

The NCI’s new initiative will be, as aforementioned, the first step toward the establishment of a full Cancer Knowledge Commons, relative to the US National Academy report on Precision Medicine, and will be coordinated with the National Institutes of Health’s (Bethesda, MD, USA) Big Data to Knowledge (BD2K) initiative and other pertinent activities in large-scale data analysis.

Related Links:

US National Cancer Institute



Channels

Genomics/Proteomics

view channel
Image: Biopsy of small bowel showing celiac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts (Photo courtesy of Wikimedia Commons).

Reduced Elafin Levels Associated with Celiac Disease Bowel Inflammation

Levels of the enzyme elafin, an endogenous serine protease inhibitor, were lower in the small intestinal epithelium of patients with active celiac disease (CD) as compared to similar tissue from control patients.... Read more

Drug Discovery

view channel

Retinoic Acid Prevents Precancerous Breast Cells from Progressing to Full-Blown Cancer

Retinoic acid, a derivative of vitamin A, was found to prevent pre-cancerous breast cells from progressing to full-blown cancer but did not have any effect on breast tumor cells. Investigators at Thomas Jefferson University (Philadelphia, PA, USA) worked with a novel breast cancer model that had been developed by treating... Read more

Biochemistry

view channel

Mitochondrial Cause of Aging Can Be Reversed

Researchers have found a cause of aging in lab animals that can be reversed, possibly providing an avenue for new treatments for age-related diseases including type 2 diabetes, cancer, muscle wasting, and inflammatory diseases. The researchers plan to begin human trials late 2014. The study, which was published December... Read more

Therapeutics

view channel

Cytokine Identified That Causes Mucositis in Cancer Therapy Patients

The action of the cytokine interleukin 1-beta (IL-1beta) has been found to underlie the onset of mucositis, a common, severe side effect of chemotherapy and irradiation of cancer patients. Mucositis occurs as a result of cell death in reaction to chemo- or radiotherapy. The mucosal lining of the mouth becomes thin, may... Read more

Business

view channel

Analytical Sciences Trade Fair Declared a Rousing Success

Organizers of this year's 24th "analytica" biosciences trade fair have reported significant increases in both the number of visitors and exhibitors compared to the 2012 event. The analytica trade fair for laboratory technology, analysis, and biotechnology has been held at the Munich (Germany) Trade Fair Center every... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.