Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING
GLOBETECH PUBLISHING
JIB

New Multimode Microplate Reader Delivers High Resolution Performance

By BiotechDaily International staff writers
Posted on 07 Oct 2013
Image: The Mithras2 LB 943 Multimode Monochromator Reader (Photo courtesy of Berthold Technologies).
Image: The Mithras2 LB 943 Multimode Monochromator Reader (Photo courtesy of Berthold Technologies).
A newly available next generation microplate reader performs luminescence, fluorescence, and absorbance measurements with the sensitivity and resolution usually obtained only from separate, dedicated instruments.

The Berthold Technologies (Bad Wildbad, Germany) Mithras2 LB943 microplate reader is a high-end multimode reader based on monochromator technology. The instrument is equipped with two double monochromators with high blocking efficiency and high f-number (increased transmission) for filter free absorbance and fluorescence measurements.

The Mithras2 was designed to carry out an impressive variety of assays including Luminescence, BRET (Bioluminescence Resonance Energy Transfer), fluorescence, FRET (Fluorescence Resonance Energy Transfer), fluorescence polarization (FP), UV/VIS absorbance, time-resolved fluorescence, and time-resolved-FRET. To accomplish these varied tasks the instrument was designed with a proprietary optical system consisting of separate paths for different reading technologies, thus offering quality analysis usually obtained only from separate dedicated instruments.

The instrument can be configured for up to four reagent injectors programmed to dispense multiple activators or detection reagents with user-adjustable volumes at any time during the measurement process. The injectors are based on proprietary JET injection technology that delivers superior accuracy and precision. Variable injections speeds and "bio-friendly" materials enable injection of live cells.

The Mitras2 can be used to measure enzyme activities, phagocytosis, calcium flux, cell viability, apoptosis, immunoassays, protein and nucleic acid concentrations, and protein-protein interactions. Single and multiple endpoint measurements as well as kinetic and scanning measurements can be performed. The data can be displayed numerically and graphically and may be printed or exported to a spreadsheet.

Related Links:

Berthold Technologies




comments powered by Disqus

Channels

Genomics/Proteomics

view channel
Image: This micrograph depicts the presence of aerobic Gram-negative Neisseria meningitidis diplococcal bacteria; magnification 1150x (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Infection by Meningitis Bacteria Depends on Dimerization State of Certain Host Cell Proteins

A team of molecular microbiologists has untangled the complex three-way interaction between the non-integrin laminin receptor (LAMR1), galectin-3 (Gal-2), and the pathogenic bacterium Neisseria meningitidis.... Read more

Drug Discovery

view channel

Molecule in Green Tea Used as Carrier for Anticancer Proteins

A molecule that is a key ingredient in green tea can be employed as a carrier for anticancer proteins, forming a stable and effective therapeutic nanocomplex. This new discovery could help to construct better drug-delivery systems. Some cancer treatments depend on medication comprising the therapeutic drug and a carrier... Read more

Business

view channel

Interest in Commercial Applications for Proteomics Continues to Grow

Increasing interest in the field of proteomics has led to a series of agreements between private proteomic companies and academic institutions as well as deals between pharmaceutical companies and novel proteomics innovator biotech companies. Proteomics is the study of the structure and function of proteins.... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.