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Biochemistry

Neutrophil Subtypes Play Different Roles During Cancer Development

Evidence presented in a recent paper suggests that the role of neutrophils in tumor biology may need to be reconsidered. More...
01 Feb 2015

Possible New Target Found for Treating Brain Inflammation

Scientists have identified an enzyme that produces a class of inflammatory lipid molecules in the brain. Abnormally high levels of these molecules appear to cause a rare inherited eurodegenerative disorder, and that disorder now may be treatable if researchers can develop suitable drug candidates that suppress this enzyme.  More...
28 Jan 2015
Image: Induced pluripotent stem (iPS) cells, which act very much like embryonic stem cells, are shown growing into heart cells (blue) and nerve cells (green) (Photo courtesy of Gladstone Institutes/Chris Goodfellow).

Methodology Devised to Improve Stem Cell Reprogramming

In a study that provides scientists with a critical new determination of stem cell development and its role in disease, researchers have established a first-of-its-kind approach that outlines the stages by which specialized cells are reprogrammed into stem cells resembling those found in embryos. The research could have wide ranging, long-term implications in enhancing disease modeling and devising new therapies for patients.  More...
27 Jan 2015

New Device Designed to See Communication between Immune Cells

The immune system is a complicated network of many different cells working together to defend against invaders. Effectively combating an infection depends on the interactions between these cells. A new device offers a much more detailed image of that specific cellular communication. Using this device, which captures pairs of cells and collects data on each as they interact with each other, researchers have already learned more about how T cells become activated during infection. More...
21 Jan 2015

Blocking Enzyme Switch Turns Off Tumor Growth in T-Cell Acute Lymphoblastic Leukemia

Researchers recently reported that blocking the action of an enzyme “switch” needed to activate tumor growth is emerging as a practical strategy for treating T-cell acute lymphoblastic leukemia.  More...
04 Nov 2014
Inflammatory response and damage to the intenstinal wall (left) could be prevented by injecting TRPV1-deficient T-cells (right). Photo courtesy of Nature Immunulogy, Bertin et al.).

Discovery of Pain Receptor on T-cells Could Help Treat Autoimmune Disorders

Researchers have discovered that T-cells are activated by a pain receptor. The new findings revealed that the receptor helps control intestinal inflammation in mice and that its activity can be adjusted, providing a potential new target for treating certain autoimmune disorders, such as Crohn’s disease and possibly multiple sclerosis.  More...
19 Oct 2014

Acoustic Device Designed to Separate Tumor Cells from Blood Cells Could Help Assess Cancer’s Spread

Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel.   More...
23 Sep 2014


The Biochemistry channel of BioResearch covers the chemical process of biomolecules and biochemical processes from enzyme-catalyzed reactions to signal transduction, from the biochemistry of cell metabolism down to cell-membrane transport.
 
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