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Events

05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017
12 Apr 2017 - 14 Apr 2017

Therapeutics

Image: Photograph (left) and optical microscopic (right) images of the new hydrogels with polyethylene glycol (PEG) microstructures developed to enable burst-free sustained-release of PEGylated protein drugs such as PEGylated interferon (Photo courtesy of A*STAR’s Institute of Bioengineering and Nanotechnology).

New Gel Extends Release Half-Life of PEGylated Drugs

Researchers have developed a first-of-its-kind hydrogel for more effective long-term drug delivery that would also reduce side-effects and discomfort for patients. Their proof-of-concept study showed effectiveness of the hydrogel with the hepatitis C drug PEGylated-interferon.  More...
08 Jul 2015
Image: A photmicrograph of medium spiny neurons (yellow) with nuclear inclusions (orange), which occur as part of the Huntington\'s disease process. Several neurons are colored yellow and have a large central core with up to two dozen tendrils branching out of them. The core of the neuron in the foreground contains an orange blob about a quarter of its diameter (Photo courtesy of Wikimedia Commons).

Seeding Assay May Boost Search for Huntington's Disease Drugs

An assay technique that measures seeding of mutant huntingtin aggregates in cerebral spinal fluid may identify individuals with Huntington's disease that have not yet become symptomatic and may be used to evaluate the efficacy of new drug treatments for the disease.  More...
07 Jul 2015
Image: Illustration of the 3D structure of antibody complexes for all four serotypes bound to the Dengue virus envelope protein (Image courtesy of Institut Pasteur).

Achilles Heel in Dengue Virus Discovered

Researchers have found new hope for a vaccine against dengue fever after discovering a vulnerable site on the surface of the Dengue virus that is targeted by the only broadly neutralizing human antibodies identified to date.   More...
26 Apr 2015
Image: Low-temperature plasmas are formed in a chamber like the one shown in the photo by applying a high electric field across a gas at atmospheric pressure and room temperature (Photo courtesy of the University of York).

Low-Temperature Plasma Treatment Kills Prostate Cancer Cells

By combining physics and biology a team of British cancer researchers has shown that low-temperature plasma treatment kills prostate cancer cells in culture and may warrant development into a therapeutic tool to replace radiation and photodynamic methods.  More...
22 Apr 2015
Image: A protein — shown in red, white, and blue — typically coats the genome of the Ebolavirus, providing protection from enzymes that can destroy the virus’s genetic material. This protein coat is removed to allow the virus to replicate its genome in infected cells. Interfering with the removal and the return of the protein coat to the viral genome can kill the Ebola virus, a discovery that opens the door to more effective treatments (Photo courtesy of Washington University School of Medicine).

Ebolavirus Nucleoprotein Suggested as Possible Drug Target

A team of molecular virologists has isolated and characterized a peptide from Ebolavirus that is critical to the pathogen's ability to reproduce inside infected cells.  More...
19 Apr 2015

PROPPR Trial Supports Use of Transfusion Protocol Initially Developed for Battlefield Trauma Patients

In a groundbreaking multisite prospective clinical trial, the damage control resuscitation protocol for massive blood transfusion significantly improved severe trauma patient outcome from hemorrhagic shock, when compared to another commonly used protocol.  More...
04 Mar 2015
Image: Plaque abnormalities in the brain of a mouse (left), and brain tissue treated with MR imaging-guided focused ultrasound (right) (Photo courtesy of Kullervo Hynynen, Sunnybrook Research Institute).

Alzheimer's Disease Symptoms Reversed for the First Time

Researchers at the Sunnybrook Research Institute, have found a way to reverse some of the symptoms of Alzheimer's disease, using Magnetic Resonance imaging-guided focused ultrasound.   More...
24 Feb 2015


BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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