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Biochemistry

Inflammatory response and damage to the intenstinal wall (left) could be prevented by injecting TRPV1-deficient T-cells (right). Photo courtesy of Nature Immunulogy, Bertin et al.).

Discovery of Pain Receptor on T-cells Could Help Treat Autoimmune Disorders

Researchers have discovered that T-cells are activated by a pain receptor. The new findings revealed that the receptor helps control intestinal inflammation in mice and that its activity can be adjusted, providing a potential new target for treating certain autoimmune disorders, such as Crohn’s disease and possibly multiple sclerosis.  More...
19 Oct 2014

Acoustic Device Designed to Separate Tumor Cells from Blood Cells Could Help Assess Cancer’s Spread

Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel.   More...
23 Sep 2014

Two-Dimensional Infrared Spectroscopy Offers Clues into Amyloid Disease Mechanisms

New data revealed by using two-dimensional infrared spectroscopy shows an intermediate structure during the amylin aggregation pathway that may clarify toxicity, offering new strategies for interventions.   More...
04 Aug 2014
Image: Migrating embryonic neural crest cells (Photo courtesy of UCL - University College London).

Blocking Cell Movement Explored to Stop the Spread of Cancer

Learning more about how cells travel through the body could lead to innovative new treatments to block cancer cells from metastasizing and causing secondary tumors, according to new research.  More...
14 Jul 2014
Image: Mouse fibroblast shows Clec16a (red), the lysosome protein Lamp1 (green), the autophagosome protein LC3 (blue), and DNA (gray). The yellow overlap of the red and green stains shows that Clec16a resides in the endolysosomal compartment, part of the cellular disposal system used in mitophagy (Photo courtesy of the University of Pennsylvania).

Diabetes Linked to Faulty Mitochondria Disposal Pathway

A molecular pathway that regulates the disposal of defective mitochondria has been cited as a potential target for prevention and control of diabetes and certain other diseases.  More...
08 Jul 2014

Small-Scale Incubator Microscope Designed to Study Cells in Time Lapse

German scientists have now devised innovative technology that combines the functions of both incubators and microscopes in a compact small-scale system.   More...
11 Jun 2014
Image: A microscopic image of erythroblasts which are the bone marrow cells that secrete erythroferrone (Photo courtesy of UCLA - University of California, Los Angeles).

Erythroferrone Frees Up Iron for Red Blood Cell Production by Inhibiting Hepcidin

A recent paper outlined a novel biochemical pathway in the bone marrow that regulates the increase production of red blood cells that are required following blood loss due to hemorrhage or anemia.  More...
11 Jun 2014


The Biochemistry channel of BioResearch covers the chemical process of biomolecules and biochemical processes from enzyme-catalyzed reactions to signal transduction, from the biochemistry of cell metabolism down to cell-membrane transport.
 
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