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12 Apr 2017 - 14 Apr 2017
22 Apr 2017 - 26 Apr 2017
New products on world’s medical product marketplace:

Genomics/Proteomics

Image: A ball and stick model of artemisinin (Photo courtesy of Wikimedia Commons).

Artemisinin Hastens TB Cure by Preventing Bacteria from Becoming Dormant

A team of microbiologists has found that a drug usually used to treat malaria can shorten the time needed to treat tuberculosis (TB) by preventing the causative organism (Mycobacterium tuberculosis) from entering a dormant, drug resistant state. More...
05 Jan 2017
Image: Two mitochondria from mammalian lung tissue displaying their matrix and membranes as shown by electron microscopy (Photo courtesy of Wikimedia Commons).

Crucial Mitophagy Protein Identified

A receptor protein located on the inner mitochondrial membrane has been identified as a critical initiator of the process of mitochondrial destruction known as mitophagy. More...
05 Jan 2017
Image: Synthetic cardiac stem cells could offer therapeutic benefits without associated risks (Photo courtesy of Alice Harvey, North Carolina State University).

Artificial Stem Cells Promote Cardiac Repair in Mouse Model

A team of biomedical engineers created a novel class of artificial stem cells that mimic the function of cardiac stem cells and aid repair of damaged heart tissue without danger of adverse immune response or the possibility of tumor generation. More...
05 Jan 2017
Image: Mutations associated with Alzheimer\'s disease alter the surface structure of the TREM2 protein, while mutations linked to Nasu-Hakola disease disrupt the protein\'s interior. Such alterations may impair TREM2\'s normal role in removing cellular waste via phagocytosis (Photo courtesy of Daniel L. Kober, Washington University School of Medicine).

Single Mutation Causes Two Separate Neurodegenerative Diseases

Resolution of the X-ray crystallography structure of variants of TREM2 (Triggering receptor expressed on myeloid cells 2) protein revealed that mutations responsible for Nasu-Hakola disease were buried deep within the core of the folded protein, while mutations associated with Alzheimer’s disease resided on the surface of the protein. More...
04 Jan 2017
Image: A homology model of the TRPV1 calcium ion channel (Photo courtesy of Wikimedia Commons).

Activation of Channel Proteins Slows Cancer Cell Growth and Impairs Metastatic Capability

A team of German researchers working with an aggressive breast cancer cell line showed that activation of TRPV1, a transient receptor potential channels protein, caused significant inhibition of cancer cell growth and induced apoptosis and necrosis. More...
04 Jan 2017
Image: High molecular weight tau bands (about 80kDa) can be visualized, with greater immunoreactivity, in patients with AD compared with healthy subjects (Photo courtesy of Dr. Ricardo B. Maccioni, University of Chile).

Assessment of Tau Protein Status for Early Detection of Alzheimer's Disease

The ratio of normal to aggregated tau protein found in blood platelets has been suggested as a biomarker that could be used for the early detection of Alzheimer's disease. More...
03 Jan 2017
Image: The molecular model of the ARID1A protein (Photo courtesy of Wikimedia Commons).

ARID1A Mutations Linked to ATR Anti-Cancer Drug Sensitivity

A team of British cancer researchers suggested in a recent paper that screening for mutations in the ARID1A (AT-rich interactive domain-containing protein 1A) gene could aid in identifying patients with tumors sensitive to the ATR inhibitor class of anti-cancer drugs. More...
03 Jan 2017

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BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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