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Genomics/Proteomics

Image: Micrograph showing human chromosomes (grey) capped by telomeres (white) (Photo courtesy of the US Department of Energy Human Genome Program).

Experimental Cancer Drug Disrupts Telomerase Function

Cancer researchers have published a detailed study of the potential chemotherapeutic drug 6-thio-2'-deoxyguanosine, a potent inhibitor of the enzyme telomerase.  More...
12 Jan 2015

Genome Editing Application Has Potential in Modifying Human Stem Cells

A unique genome editing tool known as CRISPR has been used by researchers for several years to fit, replace, disrupt, or add to sequences of an organism’s DNA. Now, scientists have shown that the system also precisely and effectively changes human stem cells, which could become a new advance in the use of stem cells for treatment and disease research.  More...
12 Jan 2015

Protein Bioengineering Applications May Offer a Treatment for Huntington’s Disease, Improving Motor Function and Reducing Brain Shrinkage

Researchers have improved motor function and brain abnormalities in lab animals with a form of Huntington’s disease, a severe neurodegenerative disorder, by modifying the levels of a key signaling protein. This new findings may become the basis of a new treatment for individuals suffering from this lethal, progressive disease.  More...
11 Jan 2015
Image: Color-coded image shows the surface view of enterovirus D68, which has stricken children with serious respiratory infections and might be associated with polio-like symptoms. Red regions are the highest peaks, and the lowest portions are blue. In the black-and-white background are actual electron microscopy images of the EV-D68 virus (Photo courtesy of Purdue University).

Study Suggests Pleconaril Has Potential to Treat EV-D68 Infection

The antiviral drug pleconaril effectively blocks the spread of laboratory strains of EV-D68 virus but fails to protect against the strains currently causing an outbreak of childhood respiratory disease in the United States.  More...
11 Jan 2015
Image: N-Glycolylneuraminic acid (Neu5Gc) (Photo courtesy of Wikimedia Commons).

Sugar Found in Red Meat Causes Chronic Inflammation in Human-Like Mouse Model

Chronic inflammation in humans, which has been linked to tumor formation as well as development of other syndromes such as atherosclerosis and type II diabetes, may be a response to red meat in the diet that contains the sugar N-Glycolylneuraminic acid.  More...
06 Jan 2015

Nematode May Hold Clues into Aging Elixir

A new discovery may hold new strategies to slow the aging process.  More...
06 Jan 2015
Image: Dysregulation of the protein Chi3l1 allows melanoma (black specks) to spread to the lungs of mice. Chi3l1 was relatively unchecked in the lung on the right, compared to the lung on the left, which had much less spread of the cancer (Photo courtesy of Brown University).

Novel Molecular Pathway Controls Metastasis in Mouse Melanoma Model

Cancer researchers have found that the protein Chi3l1 stimulates formation of metastases in a mouse model under the regulatory influence of the protein semaphorin 7a and its receptors.  More...
05 Jan 2015


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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