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10 Oct 2016 - 12 Oct 2016
12 Nov 2016 - 16 Nov 2016


Image: An enhanced image of the Zika virus based on cryo-electron microscope data (Photo courtesy of Dr. Daved Fremont, Washington University School of Medicine).

Anti-Zika Virus Monoclonal Antibodies to Aid in Vaccine Development

Highly specific monoclonal antibodies have been produced that may play a crucial role in the development of a vaccine to treat Zika virus (ZIKV) infection or as the basis for rapid diagnostic tests to detect it. More...
11 Aug 2016
Image: Digitally colorized transmission electron micrograph (TEM) of Zika virus, which is a member of the family Flaviviridae. Virus particles, here colored red, are 40 nanometers in diameter, with an outer envelope, and an inner dense core (Photo courtesy of the CDC).

Solving the 3D Structure of Zika Virus NS1 May Aid in Vaccine Development

A team of molecular virologists has established the crystal structure of the full-length Zika virus NS1 (nonstructural protein 1), a critical virulence protein that functions in genome replication and host immune-system modulation. More...
10 Aug 2016
Image: A photomicrograph of lung tissue infected by pneumonia bacteria (Photo courtesy of Alexandra Bettina, University of Virginia).

Cytokine Required by Immune Cells in Lungs to Defend Against Pneumonia Infection

The cytokine macrophage-colony stimulating factor (M-CSF) was been found to play a critical role in the ability of immune cells in the lung to defend against infection by pneumonia-causing bacteria. More...
09 Aug 2016
Image: The flash-drive-sized device contains two layers of human cells that model the interface between mother and fetus. Microfluidic channels on either side of those layers allow studies of how molecules are transported through, or are blocked by, that interface (Photo courtesy of the University of Pennsylvania).

Organ-on-a-Chip Device Mimics Structure and Function of Human Placental Barrier

A novel lab-on-a-chip device mimics the structure and function of the human placental barrier and allows researchers to carry out in vitro studies on factors influencing fetal development. More...
09 Aug 2016
Image: From left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning due to HGPS that were rebooted by the embryonic stem cell gene NANOG (Photo courtesy of Stelios Andreadis, University at Buffalo).

Expression of Stem Cell Gene Restores Contractile Function to Aged Muscle Cells

Transplanting a stem cell gene into aged muscle cells reversed many indicators of cellular senescence and completely restored the cells' ability to generate contractile force. More...
08 Aug 2016
Image: A diagram of the RNA-binding region of Rbfox2, shown in grey, attached to part of its natural RNA target, depicted in orange, green, blue, and red (Photo courtesy of Yu Chen, Fan Yang and Gabriele Varani, University of Washington).

Novel Method Described for Blocking Action of Cancer-Promoting MicroRNA

A team of molecular biologists has described a novel method for selectively blocking the activity of a cancer-promoting microRNA. More...
08 Aug 2016
Image: In this photomicrograph, the color orange indicates where tau protein has traveled from one neuron to another (Photo courtesy of Dr. Karen E. Duff, Columbia University Medical Center).

Increased Neuronal Activity Stimulates Spread of Tau Proteins in the Brain

Neurodegenerative disease researchers have found that tau proteins released from donor neurons can transfer to recipient cells via the medium, suggesting that at least one mechanism by which tau can transfer in the brain is via the extracellular space. More...
04 Aug 2016

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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