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Genomics/Proteomics

Cholesterol Metabolite Contributes to Buildup of Atherosclerotic Plaques

A recent paper described the mechanism by which the cholesterol metabolite 27-hydroxycholesterol contributes to the development of the fatty plaques that characterize atherosclerosis.  More...
01 Jul 2014

Nanoscale Velcro Proteins Discovered to Be Used for Molecule Transport

Scientists have discovered that proteins found within the nuclear pore function similar to a “Velcro” snap that can be used for controlled and selective transport of particles.   More...
01 Jul 2014

Mutations in the Apolipoprotein C3 Gene Lower Triglyceride Levels and Reduce Heart Disease Risk

Mutations, which prevent the normal functioning of the APOC3 gene, lower blood triglyceride levels and reduce the risk of developing coronary artery disease.  More...
30 Jun 2014

Human Proteome Catalog Created for Speeding Research and Diagnostic Development

An international team of researchers recently created an initial catalog of the human “proteome,” in an effort to provide a protein equivalent of the Human Genome Project.  More...
30 Jun 2014
Image: This image shows a microscopic view of the high concentration (red) of gamma-aminobutyric acid (GABA) in the reactive astrocytes (green) in the human brain with Alzheimer\'s disease (Photo courtesy of Dr. Gong Chen, Pennsylvania State University).

High GABA Level Astrocytes Are a New Alzheimer's Disease Biomarker and Drug Target

Cells comprising an abnormal class of brain cells called reactive astrocytes contain high levels of the inhibitory neurotransmitter gamma-aminobutyric acid and are being eyed by researchers as a potential biomarker and drug target for Alzheimer's disease.   More...
25 Jun 2014
Image: Pictured is mouse optic nerve and retina, responsible for relaying information from the eye to the brain. The tissue has been fluorescently stained to reveal the distribution of astrocytes (yellow), retinal ganglion cell axons (purple), myelin (green) and nuclei (cyan). Retinal ganglion cell axons transfer mitochondria to adjacent astrocytes in the optic nerve head behind the retina. Astrocytes degrade the mitochondria in a process called transmitophagy (Photo courtesy of the University of California, San Diego).

Certain Optic Cells Export Their Damaged Mitochondria for Destruction Elsewhere

A recent paper revealed that certain cells in the eye transfer damaged mitochondria to neighboring cells for destruction and recycling.  More...
25 Jun 2014

Rainbow Mouse Model Reveals Secrets of Kidney Regeneration

The ability of the kidney to regenerate following disease or injury has been linked to the activation of the WNT signaling pathway and the generation of segment-specific fate-restricted clones.  More...
24 Jun 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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