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Researchers Stress Cancer Cells for Better Treatment Options

Employing metabolic stress to destroy cancer cells could create new approaches for better targeted therapies that will not hurt normal cells and have no unpleasant side effects.   More...
10 Dec 2014
Image: Color coding of genes activated in the liver (yellow) as waves of their activation relative to the time of day. Zeitbeger times (ZT):  ZT0= 7 am, ZT3=10 am, ZT6=1 pm, etc. (Photo courtesy of Dr. Bin Fang, Perelman School of Medicine, University of Pennsylvania).

Scientists Unwind More Mysteries of the Cellular Clock

A new study surveying circadian gene expression provides a new understanding of how one clock leads to at least 8 different subclocks, and may suggest a new venue for drug treatment of clock-based metabolic disorders.  More...
08 Dec 2014

Newly Discovered Protein Complex Pathway Found to Be Key to Radiation-Induced Antitumor Immunity

A recently discovered protein complex called STimulator of INterferon Genes plays a key role in detecting the presence of tumor cells and triggers an aggressive antitumor response by the body’s innate immune system.  More...
02 Dec 2014

Second Protein Identified for Common Kidney Failure

An international team of researchers has found a second protein, THSD7A, associated with a common form of kidney failure—the autoimmune “membranous nephropathy.” The discovery is likely to provide an important new biomarker for the disease.  More...
01 Dec 2014

Cholesterol Levels in Later Life Depend in Part on Apolipoprotein E Allele Status

Variations in the APOE gene modify the rise and fall of serum cholesterol levels from midlife to late life, and in order to efficiently modify cholesterol through the life span, it is important that the physician takes into account the patient's APOE allele status.  More...
01 Dec 2014
Image: Structure of a typical neuron dendrite (Photo courtesy of Wikimedia Commons).

Protein That Causes Damage in Early Brain Development Linked to Schizophrenia

Overexpression of a protein encoded by a susceptibility gene for schizophrenia was found to cause defective cortical patterning, which results in pathological structural changes in the developing brain.  More...
01 Dec 2014

Blocking the Thromboxane Receptor Prevents Alzheimer's Disease in Mouse Model

A recent study carried out on a transgenic mouse model of Alzheimer's disease identified the thromboxane receptor as an active contributor to the development of the disease and a feasible target for drugs to treat it.  More...
30 Nov 2014

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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