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Genomics/Proteomics

Image: Diagram illustrates the innovative process that could lead to more effective drugs against influenza infection (Photo courtesy of the Hebrew University of Jerusalem).

Researchers Show How the Influenza Virus Blocks Natural Killer Cell Recognition

A team of molecular virologists has described how the influenza virus evolved a defense mechanism to protect it from attack by the immune system's natural killer cells.  More...
31 Aug 2014

Genome-Wide Mutation-Searching Computational Software Designed for Genomic Medicine

Analysis software cross-references a patient’s symptoms with his genome sequence to help physicians in the diagnosis of disease.   More...
31 Aug 2014
SLAS - Society for Laboratory Automation and Screening
RANDOX LABORATORIES
BIOSIGMA S.R.L.
Image: Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond. They are found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals (Photo courtesy of Wikimedia Commons).

Elevated Levels of IgG2 Antibodies Protect Some Types of Gram-Negative Bacteria

The finding that an overabundance of a certain class of antibodies protects some bacteria from the effects of antibiotics has marked implications for our understanding of the protection generated by natural infections and for the design of vaccines, which should avoid inducing such inhibitory antibodies.  More...
27 Aug 2014

Partnership Established to Decode Bowel Disease

23andMe, a personal genetics company, is collaborating with Pfizer, in which the companies will seek to enroll 10,000 people with inflammatory bowel disease in a research project designed to explore the genetic factors associated with the onset, progression, severity, and response to treatments for IBD.  More...
25 Aug 2014
Image: Microscopic view of a section of mouse brain shows tiny clusters of tumor cells growing along existing brain blood vessels (Photo courtesy of the University of Michigan).

Brain Tumors Grow by Tapping Preexisting Blood Vessels for Nutrients

Findings from a new study on how tumors grow and spread in the brain may cause cancer researchers to rethink treatment options based on drugs that block angiogenesis.  More...
24 Aug 2014
Image: The presence of p45 (green staining) and p75 (red staining) indicates that motor neurons increase both p45 and p75 expression after sciatic nerve injury in an animal (Photo courtesy of the Salk Institute for Biological Studies).

Blocking Nerve Growth Factor Receptor Enables Human Nervous System Regeneration

The mystery of why the human nervous system is unable to regenerate may have been at least partially solved with the identification of a protein called p75 that seems to block the repair of damaged nerve cells.   More...
20 Aug 2014
Image: In mice whose brain tumor cells (in green) could not make galectin-1, the body’s immune system was able to recognize and attack the cells, causing them to die. In this microscope image, the orange areas show where tumor cells had died in just the first three days after the tumor was implanted in the brain. Six days later, the tumor had been eradicated (Photo courtesy of the University of Michigan).

Surface Protein Protects Brain Tumor Cells from Immune Attack

Malignant glioma brain tumor cells suppress the natural killer cell immune response by over expressing the surface protein galectin-1, and suppression of this protein renders the tumor cells susceptible to destruction by the immune system.   More...
19 Aug 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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