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09 Apr 2018 - 12 Apr 2018
10 Apr 2018 - 13 Apr 2018


Image: A synthetic, injectable hydrogel developed at Rice University boosts the toxicity of a new class of cancer-fighting immunotherapy drugs. This scanning electron microscopy image shows the self-assembled nanofibers that make up the hydrogel (Photo courtesy of Hartgerink Research Group, Rice University).

Hydrogel Developed for Controlled Release of Immunotherapeutic Drugs

Cancer researchers have developed an injectable hydrogel designed to expedite the controlled release of a cyclic dinucleotide drug for enhanced cancer immunotherapy. More...
21 Mar 2018
Image: An optical readout of bound NADH fraction in control (left), and carbonyl cyanide m-chlorophenyl hydrazine treated (right) HL-1 cardiomyocytes (Photo courtesy of Irene Georgakoudi and Zhiyi Liu, Tufts University).

Microscopy Technique Monitors Biomarkers of Subcellular Alterations

A fluorescence microscopy technique has been adapted for monitoring subcellular functional and structural alterations that may be associated with changes in cellular metabolism indicative of the development and progression of numerous diseases, including cancer, diabetes, and cardiovascular and neurodegenerative disorders. More...
20 Mar 2018
Image: The process of extracting proteolipid material, protein enrichment, and vesicular formulation of leukosomes (Photo courtesy of the Houston Methodist Research Institute).

Biomimetic Nanoparticles Prove Effective for Biotherapeutic Drug Transport

Nanoparticles coated with proteins from immune system leukocytes were shown to provide an effective transport and delivery system for biotherapeutic drugs. More...
19 Mar 2018
Image: Mouse (left) and human (right) alveolar progenitor cells grow into large lung organoids in culture, and make multiple types of epithelial cells including gas exchange type 1 cells (red) and surfactant-producing type 2 cells (green) (Photo courtesy of the Morrisey Laboratory, University of Pennsylvania).

Lung Progenitor Cells Enable Culture of 3D Organoids for Studies

An in vitro system for growth of three-dimensional lung organoids was used to characterize a line of alveolar stem cells that plays a critical role in repairing lung tissues damaged by severe influenza or other respiratory ailments such as chronic obstructive pulmonary disease (COPD). More...
15 Mar 2018
Image: The crystal Structure of K-Ras G12C (Photo courtesy of the Yale Cancer Center).

New Cancer Treatments Aimed at Preventing Drug Resistance

Cancer researchers have proposed a method for preventing development of resistance to chemotherapy that targets a mutation that appears spontaneously in certain lung tumors. More...
14 Mar 2018
Image: Left: Genetic differences are easily seen across individuals of different ancestries. Each point represents a person colored by his ancestry, and the graph is a reduction of the complex genetics vector of each person into two dimensions. Right: No differences are seen in the microbiome of individuals of different ancestries. Same as left, but the plot is of the microbiome reduced to two dimensions. Coloring is by ancestries and no separation can be seen (Photo courtesy of the Weizmann Institute of Science).

Environmental Influences Important in Determining Microbiome Composition

The contribution of an individual's genetic heritage is much less important than environmental factors in determining the makeup of his or her personal microbiome. More...
13 Mar 2018
Image: CRISPR/Cas9 is a reprogrammable DNA cutting machine that is being used to edit genomes in many organisms for research purposes (Photo courtesy of Advanced Analytical Technologies).

Naturally Occurring CRISPR/Cas9 Cuts DNA and RNA

A team of molecular microbiologists has identified a naturally occurring version of the CRISPR/Cas9 gene-editing complex that cuts both DNA and RNA with equal proficiency. More...
12 Mar 2018

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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