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Drug Discovery

Image: Tubular shaped polymersomes - plastic nanoparticles that can encapsulate drugs (Photo courtesy of the University of New South Wales).

Method Described for Producing Polymersomes of Different Shapes

A team of Australian chemists recently described a novel method for conveniently producing polymersomes of different shapes and properties. More...
15 Nov 2017
Image: A scanning electron micrograph (SEM) of the influenza virus (Photo courtesy of the CDC).

Gene Vaccine Protects Mice from Influenza Virus Strains

A team of molecular virologists protected mice from deadly infection caused by a range of influenza viruses by using a deactivated adenovirus vector to vaccinate them with a cocktail of centralized viral genes. More...
13 Nov 2017
Image: New research suggests existing antibiotics could be supercharged with quantum dots to help fight antibiotic-resistant bacteria (Photo courtesy of Getty Images).

Quantum Dot Technology Increases Efficacy of Antibiotics

A team of molecular microbiologists used quantum dot technology to increase the efficacy of antibiotics to the point where they became capable of killing strains of "antibiotic-resistant" organisms. More...
18 Oct 2017
Image: A digitally colorized transmission electron micrograph (TEM) of Zika (Photo courtesy of the CDC).

DNA-Based Vaccine Shown Safe and Effective

A team of vaccine developers used an advanced electroporation method to deliver and evaluate a new generation DNA-based vaccine designed to protect against Zika virus (ZIKV) infection. More...
16 Oct 2017
Image: A model of a potent peptide that targets influenza virus hemagglutinin and mimics the functionality of a broadly neutralizing antibody (Photo courtesy of Rameshwar U. Kadam, Ian Wilson\'s Laboratory, The Scripps Research Institute).

Potential Peptide Drugs Block Influenza Virus Activity

A recent paper described the design and structural characterization of a class of potent peptide inhibitors specifically targeted to block the activity of influenza virus hemagglutinin. More...
12 Oct 2017
Image: Ambrosia arborescens, the source of compounds toxic to cancer stem cells, is a medicinal plant with analgesic, anti-inflammatory, and antiseptic properties (Photo courtesy of Wikimedia Commons).

Anticancer Compounds Found in Medicinal Plant

Compounds isolated from the medicinal plant Ambrosia arborescens or derived from them synthetically were found to have potent toxic effect on cancer stem cells in three different breast cancer cell lines. More...
11 Oct 2017
Image: The Crystallographic structure of NR0B1 (rainbow colored) complexed with the nuclear receptor protein LRH-1 (Liver receptor homolog-1) (Photo courtesy of Wikimedia Commons).

Advanced Proteomics Strategy Identifies Promising Drug Target

Use of an advanced proteomics strategy led to the discovery of a protein in non-small-cell lung cancer (NSCLC) cells that could be targeted by low molecular weight drugs. More...
09 Oct 2017
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The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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