We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




Alzheimer's Disease Symptoms Reversed for the First Time

By MedImaging International staff writers
Posted on 24 Feb 2015
Print article
Image: Plaque abnormalities in the brain of a mouse (left), and brain tissue treated with MR imaging-guided focused ultrasound (right) (Photo courtesy of Kullervo Hynynen, Sunnybrook Research Institute).
Image: Plaque abnormalities in the brain of a mouse (left), and brain tissue treated with MR imaging-guided focused ultrasound (right) (Photo courtesy of Kullervo Hynynen, Sunnybrook Research Institute).
Researchers at the Sunnybrook Research Institute (Toronto, Canada), have found a way to reverse some of the symptoms of Alzheimer's disease, using Magnetic Resonance (MR) imaging-guided focused ultrasound.

The researchers, led by Kullervo Hynynen, PhD, of the Sunnybrook Research Institute, used transgenic (TgCRND8) mice with a condition similar to Alzheimer's disease for the study. The research was partly funded by the US National Institute of Biomedical Imaging and Bioengineering (NIBIB; Bethesda, MD, USA).

Alzheimer's Disease affects approximately 5.2 million people in the United States (US), and there is currently no treatment for the disease.

The researchers used MR imaging-guided focused ultrasound, and a microbubble contrast agent to temporarily open the Blood-Brain Barrier (BBB). This enabled more effective delivery of drugs to the brain.

Results show that the treatment improved cognition and spatial learning in the mice that could have been caused by reduced plaque, and increased neuronal plasticity, as a result of the focused ultrasound treatment. No tissue damage or negative behavioral changes in the mice was found.

Steven Krosnick, MD, of the NIBIB, said, “The results are an exciting step in the search for Alzheimer’s treatments, but there is more to be done. There are limitations on the memory tests that can be done on mice, and human cognition is significantly more complex. Hopefully these results will open doors to more research on how MR imaging-guided focused ultrasound could benefit cognition and perhaps be magnified by using other therapeutics in conjunction with this method.”

Related Links:

Sunnybrook Research Institute
[US] National Institute of Biomedical Imaging and Bioengineering (NIBIB) 


Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Imaging Table
Stille imagiQ2
Under Table Shield
3 Section Double Pivot Under Table Shield
New
Portable X-Ray Unit
AJEX240H

Print article

Channels

Nuclear Medicine

view channel
Image: PET/CT of a 60-year-old male patient with clinical suspicion of lung cancer (Photo courtesy of EJNMMI Physics)

Early 30-Minute Dynamic FDG-PET Acquisition Could Halve Lung Scan Times

F-18 FDG-PET scans are a way to look inside the body using a special dye, and these scans can be either static or dynamic. Static scans happen 60 minutes after the dye is administered into the body, showing... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more

Industry News

view channel
Image: The acquisition will expand IBA’s medical imaging quality assurance offering (Photo courtesy of Radcal)

IBA Acquires Radcal to Expand Medical Imaging Quality Assurance Offering

Ion Beam Applications S.A. (IBA, Louvain-La-Neuve, Belgium), the global leader in particle accelerator technology and a world-leading provider of dosimetry and quality assurance (QA) solutions, has entered... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.