Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING LLC
GLOBETECH MEDIA
GLOBETECH PUBLISHING LLC

Evaluating Chitosan Nerve Conduits That Bridge Sciatic Nerve Defects Visualized Using Ultrasound Imaging

By BiotechDaily International staff writers
Posted on 27 Aug 2014
Image: Ultrasound image of the morphology of a chitosan nerve conduit in a rat model of sciatic nerve defects at three weeks after modeling (Photo courtesy of Neural Regeneration Research journal).
Image: Ultrasound image of the morphology of a chitosan nerve conduit in a rat model of sciatic nerve defects at three weeks after modeling (Photo courtesy of Neural Regeneration Research journal).
The first use of ultrasound has been used by Chinese researchers to noninvasively observe the changes in chitosan nerve conduits implanted in lab rats over time.

The investigators reported that newer, simpler, and more effective ways are needed to better assess the outcomes of repair using nerve conduits in vivo. The new technology distinctly revealed whether there are unsatisfactory complications after implantation, such as fracture, collapse, bleeding, or unusual swelling of the nerve conduits; and reflected the degradation mode of the nerve conduit in vivo over time.

Ultrasound is a common noninvasive clinical detection modality that has been used in many fields. However, ultrasound has seldom been used to observe implanted nerve conduits in vivo.

Dr. Hongkui Wang and coworkers from Affiliated Hospital of Nantong University (Nantong, Jiangsu Province, China) reported on their findings July 15, 2014, in the journal Neural Regeneration Research. Ultrasound, as a noninvasive imaging modality, they noted, can be used as a supplementary observation technique during standard animal research on peripheral nerve tissue engineering.

Related Links:

Affiliated Hospital of Nantong University



Channels

Genomics/Proteomics

view channel
Image: In mice, mitochondria (green) in healthy (left) and Mfn1-deficient heart muscle cells (center) are organized in a linear arrangement, but the organelles are enlarged and disorganized in Mfn2-deficient cells (right) (Photo courtesy of the Rockefeller Press).

Cell Biologists Find That Certain Mitochondrial Diseases Stem from Coenzyme Q10 Depletion

A team of German cell biologists has linked the development of certain mitochondrial-linked diseases to depletion of the organelles' pool of coenzyme Q10 brought about by mutation in the MFN2 gene, which... Read more

Drug Discovery

view channel
Image: Molecular model of the protein Saposin C (Photo courtesy of Wikimedia Commons).

Nanovesicles Kill Human Lung Cancer Cells in Culture and in a Mouse Xenograft Model

Nanovesicles assembled from the protein Saposin C (SapC) and the phospholipid dioleoylphosphatidylserine (DOPS) were shown to be potent inhibitors of lung cancer cells in culture and in a mouse xenograft model.... Read more

Biochemistry

view channel

Possible New Target Found for Treating Brain Inflammation

Scientists have identified an enzyme that produces a class of inflammatory lipid molecules in the brain. Abnormally high levels of these molecules appear to cause a rare inherited eurodegenerative disorder, and that disorder now may be treatable if researchers can develop suitable drug candidates that suppress this enzyme.... Read more

Lab Technologies

view channel
Image: The FLUOVIEW FVMPE-RS Gantry microscope (Photo courtesy of Olympus).

New Multiphoton Laser Scanning Microscope Configurations Expand Research Potential

Two new configurations of a state-of-the-art multiphoton laser scanning microscope extend the usefulness of the instrument for examining rapidly occurring biological events and for obtaining images from... Read more

Business

view channel

Roche Acquires Signature Diagnostics to Advance Translational Research

Roche (Basel, Switzerland) will advance translational research for next generation sequencing (NGS) diagnostics by leveraging the unique expertise of Signature Diagnostics AG (Potsdam, Germany) in biobanks and development of novel NGS diagnostic assays. Signature Diagnostics is a privately held translational oncology... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.