Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING
JIB
GLOBETECH PUBLISHING

Modular Design of New Microplate Reader Encourages Modification and Upgrades

By BiotechDaily International staff writers
Posted on 25 Aug 2014
BioTek Instruments\' Synergy HTX Multi-Mode Microplate Reader
The Synergy HTX Multi-Mode Microplate Reader (Photo courtesy of BioTek)
Life science and biotech researchers now have available a state-of-the-art modular microplate reader with a wide range of capabilities from UV-visual absorbance to bottom fluorescence and luminescence.

The new BioTek Instruments, Inc. (Winooski, VT, USA) Synergy HTX Multi-Mode Microplate Reader is an entry-level multimode reader that automates UV-visual absorbance, fluorescence, luminescence, and AlphaScreen/AlphaLISA assays in 6- to 384-well microplates that can be delivered in samples as small as two microliters.

AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay Screen) is versatile assay technology developed to measuring analytes using a homogenous protocol. This technology is an example of a bead-based proximity assay and was developed from a diagnostic assay technology known as LOCI (Luminescent Oxygen Channeling Assay) where singlet oxygen molecules, generated by high energy irradiation of donor beads, travel over a constrained distance of approximately 200 nanometers) to acceptor beads. This results in excitation of a cascading series of chemical reactions, ultimately causing generation of a chemiluminescent signal. Recently, the basic AlphaScreen technology was extended in that the chemistry of the acceptor bead was modified such that emitted light is more intense and spectrally defined, thereby markedly reducing interference from biological fluid matrices (such as trace hemolysis in serum and plasma). In this format, referred to as AlphaLISA, it provides an alternative technology to classical ELISA assays and is suitable for high throughput automated fluid dispensing and detection systems.

The Synergy HTX incorporates linear and orbital shaking and Four-Zone incubation to 50 degrees Celsius with condensation control to minimize plate lid condensation. These features, coupled with an available dual reagent dispenser, make the Synergy HTX an excellent platform for biochemical and cell-based applications such as nucleic acid quantification, cell growth and toxicity assays, kinetic ELISA, and inject/read assays.

The optional dual reagent injection system automates inject/read assays such as ion channels assays or flash luminescence assays (e.g., luciferase or ATP assays). The Synergy HTX’s modular design allows upgrading supported by BioTek’s Gen5 data analysis software for advanced reader control, data analysis, graphing, exporting, and reporting. Additionally, the instrument is compatible with BioTek’s Take3 Multi-Volume Microplate that measures up to 16 two microliter samples, two BioCells, or a standard cuvette for fast and simple multivolume, multisample analysis.

Related Links:

BioTek Instruments, Inc.




Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to BiotechDaily.com and get complete access to news and events that shape the world of biotechnology.
Free digital version edition of Bio Research International sent by email on regular basis
Free print version of Bio Research International magazine
(available only outside USA and Canada).
Free and unlimited access to back issues of Bio Research International in digital format
Free Bio Research International Newsletter sent every 2 weeks containing the latest news
Free breaking news sent via email
Free access to Events Calendar
Free access to LinkXpress new product services
REGISTRATION IS FREE AND EASY!


Click here to Register

Sign in: Registered website members
Username: Password:
Forgot username/password? Click here!
Sign in: Registered magazine subscribers
Subcode: Last Name:
What is SUBCODE?


comments powered by Disqus

Channels

Genomics/Proteomics

view channel

Researchers Discover New Data on Protein Kinase A

By employing X-rays and neutron beams, a team of researchers have gleaned new information about protein kinase A (PKA), an omnipresent master control protein that helps regulate basic cellular functions such as energy consumption and interactions with neurotransmitters, hormones, and drugs. The scientists who conducted... Read more

Drug Discovery

view channel

Molecule in Green Tea Used as Carrier for Anticancer Proteins

A molecule that is a key ingredient in green tea can be employed as a carrier for anticancer proteins, forming a stable and effective therapeutic nanocomplex. This new discovery could help to construct better drug-delivery systems. Some cancer treatments depend on medication comprising the therapeutic drug and a carrier... Read more

Business

view channel

Interest in Commercial Applications for Proteomics Continues to Grow

Increasing interest in the field of proteomics has led to a series of agreements between private proteomic companies and academic institutions as well as deals between pharmaceutical companies and novel proteomics innovator biotech companies. Proteomics is the study of the structure and function of proteins.... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.