Features | Partner Sites | Information | LinkXpress
Sign In
JIB
GLOBETECH PUBLISHING
BioConferenceLive

Muscle-Pacing Technology Found to Increase Targeted Bone Volume by 30%

By BiotechDaily International staff writers
Posted on 02 Jul 2014
Image: The muscle pacing method used in the study saw the rats gain 30% of bone within the targeted areas (Photo courtesy of the University of Liverpool).
Image: The muscle pacing method used in the study saw the rats gain 30% of bone within the targeted areas (Photo courtesy of the University of Liverpool).
In an important advance for the health of older individuals, researchers have developed a new way to target bone growth. As people age, their bones lose density, and particularly in women after the menopause, become more brittle. The new technique offers the possibility of more effective treatment than currently available. The muscle-pacing technology revealed that the lab rats in the study gained 30% of bone within the targeted areas.

The new technology was developed by researchers from the University of Liverpool’s (UK) Institute of Aging and Chronic Disease. Prof. Jonathan Jarvis, from Liverpool John Moores University designed miniature muscle pacemakers that were used in the University of Liverpool labs to generate contractions in the muscles of the legs of rats over 28 days. University of Liverpool PhD student Paula Vickerton led the research. She said, “Bone disease and fragility are affecting an increasing proportion of our population. However, existing treatments are nonspecific, affecting whole bones and not just the weaker regions.”

Using the muscle-pacing technique, the rats gained 30% of bone within the targeted areas. Ms. Vickerton’s supervisor, Dr. Nathan Jeffery, said, “This method has been shown to increase the amount of bone and raises the possibility of being developed into a treatment for people who are at risk of the many complications that weakened bone can bring.”

The study’s findings were published online and slated for the August 7, 2014 issue of the journal Proceedings of the Royal Society B: Biological Sciences.

Related Links:

University of Liverpool



comments powered by Disqus

Channels

Genomics/Proteomics

view channel
Image: Microcomputed tomography images (top) and histology images (bottom) of the knees of mice fed a very high fat diet containing omega-3 fatty acid supplement (left) or only omega-6 fatty acids (right) after a knee injury. The omega-6 diet showed abnormal bone remodeling and calcified tissue formation in the joint (white arrow). The omega-6 diet also showed significant loss of cartilage (red staining, yellow arrowhead) and increased joint inflammation (Photo courtesy of Duke University).

Dietary Omega-3 Fatty Acids Moderate Severity of Osteoarthritis in a Mouse Model

Researchers working with an osteoarthritis (OA) obese mouse model found that the fat content of the animals' diet contributed more to the development or arrest of OA than did body weight.... Read more

Drug Discovery

view channel
Image: Molecular rendering of the crystal structure of parkin (Photo courtesy of Wikimedia Commons).

Cinnamon Feeding Blocks Development of Parkinson's Disease in Mouse Model

A team of neurological researchers has identified a molecular mechanism by which cinnamon acts to protect neurons from damage caused by Parkinson's disease (PD) in a mouse model of the syndrome.... Read more

Therapeutics

view channel

Vaccine Being Developed for Heart Disease Close to Reality

The world’s first vaccine for heart disease is becoming a possibility with researchers demonstrating significant arterial plaque reduction in concept testing in mice. Klaus Ley, MD, from the La Jolla Institute for Allergy and Immunology (LA Jolla, CA, USA), and a vascular immunology specialist, is leading the vaccine... Read more

Business

view channel

A Surge in IPOs Revitalize Investments for the Global Pharma and Biotech

Anti-infective drugs, oncology, and pharmaceutical contract laboratories attract the most investment up to now. The intensified private equity and venture capital (PEVC) deal activity in the global healthcare industry during the recession years, 2008–2010, witnessed a waning post-2010. However, the decline in deals... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.