Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Events

10 May 2016 - 16 May 2016
11 May 2016 - 13 May 2016

Complementary Biomolecular Analysis Instruments Available for Research and Clinical Labs

By BiotechDaily International staff writers
Posted on 31 Mar 2014
Print article
Image: b-screen is a versatile biomolecular interaction analysis tool for biomolecular arrays in standard microscope format (Photo courtesy of Biametrics GmbH).
Image: b-screen is a versatile biomolecular interaction analysis tool for biomolecular arrays in standard microscope format (Photo courtesy of Biametrics GmbH).
Two new instruments for biomolecular analysis feature coated sensor chips (microarray format and mini format respectively) and assay protocols ready to support almost any research and development application from kinetic evaluation of microarrays to online immobilization.

The instruments—b-screen and b-portable—are products of Biametrics GmbH (Tübingen, Germany). Biametrics develops and markets label-free analytical system solutions for life science applications.

Biametrics has recently launched two new product lines intended to facilitate research in diverse types of life science laboratories. The b-screen device is able to handle any standard microarray format and can detect up to 10,000 bimolecular interactions in a single measurement. The b-portable device enables high quality label-free interaction analysis under laboratory or field conditions using a smart and inexpensive technology platform.

Current applications for b-screen include bioanalytics, drug discovery, production, and quality control. Based on the same technology, b-portable is a point-of-care device for early cancer and infection detection.

The b-screen instrument provides label-free read-out of up to 10,000 spots per square centimeter. It utilizes a precise and automated microfluidics system for incubation of the microarray with the sample of interest. The instrument can be used with multiple array layouts, uses glass or plastic type substrates, and is compatible with almost any common microarray printer. No fluorescence labels are needed, which leads to assay conditions similar to the in -vivo situation combined with minimal sample pretreatment and minimized reagent consumption.

Both b-screen and b-portable may be used with different sample types such as serum or whole blood or other relevant complex matrices such as cell culture medium. Kinetic data can be obtained for almost any kind of biomolecular interaction such as those between proteins, between peptides and proteins, and between small molecules and proteins.

“With b-screen users are able to easily transfer existing microarrays directly into a label-free assay format thus gaining additional information on kinetics and thermodynamics at high precision and reliability,” said Günther Proll, managing director of Biametrics. “The device allows very low cost high-throughput screening and the applications we have established demonstrate excellent performance and outcome characteristics. We believe b-screen provides key advantages over current options like surface plasmon resonance (SPR).”

Related Links:

Biametrics GmbH



Print article

Channels

Genomics/Proteomics

view channel
Image: Drop-inoculation of Saccharomyces cerevisiae mutants on an agar plate. The assay compares the viability of different yeast mutants (Photo courtesy of Wikimedia Commons).

Defective Genome Instability Suppressing Genes May Cause Some Types of Cancer

Cancer researchers reported in a recent study that defects in the expression of genes that suppress gross chromosomal rearrangements (GCRs) were linked to more than 93% of the ovarian and 66% of the colorectal... Read more

Biochemistry

view channel
Image: Scientists had viewed ant antennae as being used only to receive information – new research has demonstrated that they also transmit critical social signals (Photo courtesy of the University of Melbourne).

Ant Antennae Communicate Vital Social ID Information

Scientists have shone new light on the complexities of insect communication with the discovery that ants not only pick up information through their antennae, but also use them to convey social signals.... Read more

Business

view channel

DNA Synthesis Specialists Acquire Advanced Software Design Capabilities

An American biotech firm that develops and produces synthetic DNA has established an international presence by purchasing an Israeli genetic design software company. Twist Bioscience Corporation (San Francisco, CA, USA), a company specializing in rapid, high-quality DNA synthesis, announced that Genome Compiler Corporation... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.