Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING
PZ HTL SA
GLOBETECH PUBLISHING

Single-Use Bioreactor Now Accommodates Wide Range of Working Volumes

By BiotechDaily International staff writers
Posted on 24 Jun 2013
Image: The UniVessel SU (right) can work in parallel with classical multiuse reaction bioreactor vessels (Photo courtesy of Sartorius Stedim Biotech).
Image: The UniVessel SU (right) can work in parallel with classical multiuse reaction bioreactor vessels (Photo courtesy of Sartorius Stedim Biotech).
Image: The UniVessel SU is preassembled and ready-to-use out of the box (Photo courtesy of Sartorius Stedim Biotech).
Image: The UniVessel SU is preassembled and ready-to-use out of the box (Photo courtesy of Sartorius Stedim Biotech).
The second generation of a highly regarded single-use bioreactor vessel with built-in pH and dissolved oxygen sensors suitable for work with mammalian, insect, and plant cell cultures was recently released for researchers in biopharmaceuticals and other life sciences.

The Sartorius Stedim Biotech (Aubagne, France) UniVessel SU is a single-use bioreactor with a choice of working volumes ranging from 0.6 to two liters. The vessel is made of USP class VI conforming polycarbonate and includes several ports for media addition, sampling, harvesting, as well as spare ports for insertion of classical sensors or other equipment. All tubing for media transfer is thermoweldable and features common Luer or MPC connectors for fast and easy connection to peripheral equipment.

Key features of the UniVessel SU are the single-use sensors for optical measurement of pH and dissolved oxygen (DO). The determination of pH and DO with the SENSOLUX system is based on fluorescence detection. Each UniVessel SU contains two sensor patches for pH and DO, respectively. The actual measurement is performed optically and noninvasively from outside the vessel. The sensor patches contain fluorescent dyes, which can be excited with light of a given wavelength. Optoelectronics integrated in the vessel holder transmit light of a particular wavelength to the sensor patches. In turn, they also transmit the luminescence response from the patches to a measuring amplifier. The sensor patches inside the UniVessel SU come precalibrated. Calibration data are located on the vessel label and can be transferred manually or by barcode reader to the calibration menu of the bioreactor controller. UniVessel SU is compatible with Sartorius BIOSTAT controllers and can also be operated with nearly any other brand of bioreactor controller.

Each UniVessel SU unit is irradiated prior to delivery and is preassembled and ready-to-use out of the box. It is designed to the same safety standards, which are required for classical multiuse bioreactors. The complete culture vessel is disposed after use, eliminating cleaning time, autoclaving, and reinstallation hassle as well as the risk of cross-contamination.

Related Links:
Sartorius Stedim Biotech




Channels

Genomics/Proteomics

view channel
Image: The TheraCyte cell encapsulation device (Photo courtesy of TheraCyte, Inc.).

Encapsulated Human-Insulin-Producing Progenitor Cells Cure Diabetes in Mouse Model

A breakthrough system that allows subcutaneous implantation of encapsulated immature pancreatic cells (beta progenitor cells) was shown to produce enough insulin to correct the symptoms of diabetes in a mouse model.... Read more

Drug Discovery

view channel
Image: Chitosan is derived from the shells of shrimp and other sea crustaceans, including Alaskan pink shrimp, pictured here (Photo courtesy of NOAA - [US] National Oceanic and Atmospheric Administration).

Chitosan Treatment Clears the Way for Antibiotics to Eliminate Recurrent Urinary Tract Infections

Recurrent urinary tract infection was successfully resolved in a mouse model by treatment with the exfoliant chitosan followed by a round of antibiotics. Bacterial urinary tract infection (UTI), most... Read more

Biochemistry

view channel

Mitochondrial Cause of Aging Can Be Reversed

Researchers have found a cause of aging in lab animals that can be reversed, possibly providing an avenue for new treatments for age-related diseases including type 2 diabetes, cancer, muscle wasting, and inflammatory diseases. The researchers plan to begin human trials late 2014. The study, which was published December... Read more

Therapeutics

view channel

Cytokine Identified That Causes Mucositis in Cancer Therapy Patients

The action of the cytokine interleukin 1-beta (IL-1beta) has been found to underlie the onset of mucositis, a common, severe side effect of chemotherapy and irradiation of cancer patients. Mucositis occurs as a result of cell death in reaction to chemo- or radiotherapy. The mucosal lining of the mouth becomes thin, may... Read more

Business

view channel

Analytical Sciences Trade Fair Declared a Rousing Success

Organizers of this year's 24th "analytica" biosciences trade fair have reported significant increases in both the number of visitors and exhibitors compared to the 2012 event. The analytica trade fair for laboratory technology, analysis, and biotechnology has been held at the Munich (Germany) Trade Fair Center every... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.