Features | Partner Sites | Information | LinkXpress
Sign In
JIB
GLOBETECH PUBLISHING
GLOBETECH PUBLISHING

New High-Sensitivity Breath Analyzer Enables Wide Range Multi-Biomarker Identification

By BiotechDaily International staff writers
Posted on 06 May 2013
Image: Microscope/Micrograph of MEMS micro-heating element with integrated CMOS electronic driver and temperature sensing circuits (Photo courtesy of Cambridge CMOS Sensors).
Image: Microscope/Micrograph of MEMS micro-heating element with integrated CMOS electronic driver and temperature sensing circuits (Photo courtesy of Cambridge CMOS Sensors).
Scientists and engineers have developed a gas-sensing technology that could enable multiple diseases and other conditions to be diagnosed and monitored using a single, highly sensitive breath analyzer.

Thousands of chemical compounds are exhaled with every breath. The infrared emitter developed by Cambridge CMOS Sensors (CCMOSS; Cambridge, UK) is a low-power, low-cost device capable of identifying more than 35 biomarkers present in exhaled human breath in concentrations as low as 1 part per million. “Noninvasive breath analysis is an area of great potential for diagnosing and monitoring a wide range of medical conditions,” said Professor Florin Udrea of the Dept. of Engineering and CCMOSS’ CEO and cofounder; “Testing is easy and painless, and can be repeated as often as needed.”

A number of breath analysis tests are currently in the R&D phase, most of which use mass spectrometry or lasers to analyze the breath for specific compounds. However, these tests can detect only a small range of compounds, so different devices are needed to detect different conditions. The CCMOSS technology differs in that it uses broadband infrared radiation to make the detection of a wide range of biomarkers possible in a single device. The miniature heaters, or microhotplates, can be heated from room temperature to 700 °C in a fraction of a second, a temperature high enough to emit infrared radiation and allow the sensing material to react with gas molecules.

Many gas molecules absorb infrared. The amount of radiation absorbed allows the gas to be identified and its concentration calculated - the basic principle behind, for example, the roadside breathalyzer test. CCMOSS’s technology, however, is far more sensitive - using broadband infrared, the gas sensor can detect wavelengths between 2 and 14 micronmeters, corresponding to a wide range of biomarkers. In order to detect different wavelengths, a filter is placed over the detector so that only infrared radiation of a particular wavelength can get through.

The company, a spinout from the University of Cambridge Department of Engineering, has been supported by seed funding from Cambridge Enterprise, the University’s commercialization arm. The CCMOSS technology is being developed for use in noninvasive medical analysis and other applications such as consumer electronics, industrial security, and automotive applications. It currently has a range of products available and is actively involved in R&D projects for next generation micro- and nanosensors.

Related Links:

University of Cambridge
Cambridge CMOS Sensors (CCMOSS)



comments powered by Disqus

Channels

Genomics/Proteomics

view channel

Researchers Discover New Data on Protein Kinase A

By employing X-rays and neutron beams, a team of researchers have gleaned new information about protein kinase A (PKA), an omnipresent master control protein that helps regulate basic cellular functions such as energy consumption and interactions with neurotransmitters, hormones, and drugs. The scientists who conducted... Read more

Drug Discovery

view channel

Molecule in Green Tea Used as Carrier for Anticancer Proteins

A molecule that is a key ingredient in green tea can be employed as a carrier for anticancer proteins, forming a stable and effective therapeutic nanocomplex. This new discovery could help to construct better drug-delivery systems. Some cancer treatments depend on medication comprising the therapeutic drug and a carrier... Read more

Business

view channel

Interest in Commercial Applications for Proteomics Continues to Grow

Increasing interest in the field of proteomics has led to a series of agreements between private proteomic companies and academic institutions as well as deals between pharmaceutical companies and novel proteomics innovator biotech companies. Proteomics is the study of the structure and function of proteins.... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.