Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING LLC
GLOBETECH PUBLISHING LLC
GLOBETECH MEDIA

Faster 3D Nanoimaging with Full Color Synchrotron Light Under Development

By BiotechDaily International staff writers
Posted on 27 Jul 2011
Researchers can now see objects more completely and faster at the nanoscale level due to utilizing the full spectrum of synchrotron light, creating avenues for faster three-dimensional (3D) nanoimaging. This new methodology will provide for enhanced nanoimaging for examining biosamples for medical research, improved drug development, and advanced materials for engineering.

Using the Advanced Photon Source at Argonne National Laboratory (Argonne, IL, USA), researchers from the ARC Center of Excellence for Coherent X-ray Science (CXS), headquartered at the University of Melbourne, Australia, revealed that by utilizing the full spectrum of colors of the synchrotron, they increased the clarity of biologic samples and obtained a 60-fold increase in the speed of imaging.

Prof. Keith Nugent, a professor of physics at the University of Melbourne and research director of CXS, said the discovery was an exciting development. “Typically for best imaging, researchers need to convert samples to crystals, but this is not always possible in all samples,” he said. “This discovery of utilizing full color synchrotron light to improve precision and speed of imaging has huge potential in the field.”

The international project was led by Dr. Brian Abbey of the University of Melbourne’s School of Physics and CXS, whose team made the discovery. “We will now be able to see things in detail at the nanoscale much more easily. It is like going from an old film camera to the latest digital SLR. The increase in speed, in particular, opens the way for us to see things faster in 3D at the nanoscale, which has previously taken an impracticably long time,” Dr. Abbey said.

The study was published in the July 2011 issue of the journal Nature Photonics.

Related Links:
Advanced Photon Source
ARC Center of Excellence for Coherent X-ray Science



Channels

Genomics/Proteomics

view channel
Image: An Austrian Research Center of Industrial Biotechnology researcher is shown working with a laboratory scale continuous antibody purification reactor (Photo courtesy of the Austrian Research Center of Industrial Biotechnology).

Continuous Purification Technique Should Significantly Reduce Antibody Production Costs

An Austrian biotechnology firm has developed a method for the continuous purification of recombinant antibodies from cultures of clarified Chinese hamster ovary (CHO) cells that promises to significantly... Read more

Drug Discovery

view channel
Image: Wafers like the one shown here are used to create “organ-on-a-chip” devices to model human tissue (Photo courtesy of Dr. Anurag Mathur, University of California, Berkeley).

Human Heart-on-a-Chip Cultures May Replace Animal Models for Drug Development and Safety Screening

Human heart cells growing in an easily monitored silicon chip culture system may one day replace animal-based model systems for drug development and safety screening. Drug discovery and development... Read more

Biochemistry

view channel
Image:  Model depiction of a novel cellular mechanism by which regulation of cryptochromes Cry1 and Cry2 enables coordination of a protective transcriptional response to DNA damage caused by genotoxic stress (Photo courtesy of the journal eLife, March 2015, Papp SJ, Huber AL, et al.).

Two Proteins Critical for Circadian Cycles Protect Cells from Mutations

Scientists have discovered that two proteins critical for maintaining healthy day-night cycles also have an unexpected role in DNA repair and protecting cells against genetic mutations that could lead... Read more

Business

view channel

“Softer” Mass Spec Techniques Gain Advantage in Biomarker Discovery

Two mass spectrometry (MS) technologies, MALDI and DESI, are increasing in applications as their effectiveness is established, according to Kalorama Information (New York, NY, USA) in its report “Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays,... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.