The BioTek Instruments, Inc. (Winooski, VT, USA) Synergy H1 Hybrid Multi-Mode Microplate Reader is a flexible monochromator-based multimode microplate reader. The monochromator optics uses a third generation quadruple-grating design that allows working at any excitation or emission wavelength with a one-nanometer step. This system supports top and bottom fluorescence intensity, UV-visible absorbance, and high-performance luminescence detection. It can handle all the standard microplate applications found in life science research laboratories.

A filter module is available as a completely independent add-on that includes its own light source, and a high performance dichroic-based wavelength selection system. With its very high optical efficiency, this module supports advanced detection modes such as Fluorescence Polarization, Time-Resolved Fluorescence and filtered luminescence (e.g.,  BRET).

A dual reagent injection system is available to automate inject/read assays such as ion channels assays or flash luminescence assays (e.g., luciferase or ATP assays). The Synergy H1 incorporates BioTek's Gen5 Data Analysis Software for advanced reader control, data analysis, graphing, exporting, and reporting. Additionally, Synergy H1 is compatible with BioTek's Take3 Multi-Volume Plate that measures up to 16 two-microliter samples, two BioCells or a standard cuvette for fast and simple multivolume, multisample analysis.

"Synergy H1 provides robust performance and for the first time makes "Hybrid Technology” available to life science, academic, and small biotechnology companies at a very competitive price,” said Gary Barush, director of marketing and sales at BioTek. "The modular architecture means that customers can easily upgrade from a monochromator-based multimode reader to a hybrid reader offering true versatility and unlimited assay use.”

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