Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH PUBLISHING LLC
GLOBETECH PUBLISHING LLC
GLOBETECH MEDIA

Protein Found to Play Key Role in Long Life

By BiotechDaily International staff writers
Posted on 02 Oct 2013
Image: The structure of the sirtuin protein Sirt1 (Photo courtesy of Shin-ichiro Imai/Washington University in St. Louis).
Image: The structure of the sirtuin protein Sirt1 (Photo courtesy of Shin-ichiro Imai/Washington University in St. Louis).
The process behind the functioning of a specific protein already believed to play a role in longevity has recently been established to do just that, lengthen lifespan.

Developmental biologist Dr. Shin-ichiro Imai, from Washington University in St. Louis (MO, USA), discovered that instead of delaying the aging process, the protein works in the brain to delay the onset of aging, thus extending youth and adding those energetic years onto one’s life span.

The researchers engineered lab mice that expressed higher than normal levels of Sirt1 in their brain and saw a substantial extension in the animals’ life spans. The scientists specifically found that Sirt1 plays a vital role in protecting against age-related declines in skeletal muscle, physical activity, body temperature, oxygen consumption, and quality of sleep. The start of the disease process in mice trigger to contract cancer was also delayed.

This new finding could help researchers better determine how to extend the life span of other mammals, including humans. The result is published September 3, 2013, in the journal Cell Metabolism.

Related Links:
Washington University in St. Louis


Channels

Biochemistry

view channel

Possible New Target Found for Treating Brain Inflammation

Scientists have identified an enzyme that produces a class of inflammatory lipid molecules in the brain. Abnormally high levels of these molecules appear to cause a rare inherited eurodegenerative disorder, and that disorder now may be treatable if researchers can develop suitable drug candidates that suppress this enzyme.... Read more

Therapeutics

view channel
Image: Cancer cells infected with tumor-targeted oncolytic virus (red). Green indicates alpha-tubulin, a cell skeleton protein. Blue is DNA in the cancer cell nuclei (Photo courtesy of Dr. Rathi Gangeswaran, Bart’s Cancer Institute).

Innovative “Viro-Immunotherapy” Designed to Kill Breast Cancer Cells

A leading scientist has devised a new treatment that employs viruses to kill breast cancer cells. The research could lead to a promising “viro-immunotherapy” for patients with triple-negative breast cancer,... Read more

Lab Technologies

view channel
Image: MIT researchers have designed a microfluidic device that allows them to precisely trap pairs of cells (one red, one green) and observe how they interact over time (Photo courtesy of Burak Dura, MIT).

New Device Designed to See Communication between Immune Cells

The immune system is a complicated network of many different cells working together to defend against invaders. Effectively combating an infection depends on the interactions between these cells.... Read more

Business

view channel

Program Designed to Provide High-Performance Computing Cluster Systems for Bioinformatics Research

Dedicated Computing (Waukesha, WI, USA), a global technology company, reported that it will be participating in the Intel Cluster Ready program to deliver integrated high-performance computing cluster solutions to the life sciences market. Powered by Intel Xeon processors, Dedicated Computing is providing a range of... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.