Features | Partner Sites | Information | LinkXpress
Sign In
JIB
GLOBETECH PUBLISHING
GLOBETECH PUBLISHING

Protein Found to Play Key Role in Long Life

By BiotechDaily International staff writers
Posted on 02 Oct 2013
Image: The structure of the sirtuin protein Sirt1 (Photo courtesy of Shin-ichiro Imai/Washington University in St. Louis).
Image: The structure of the sirtuin protein Sirt1 (Photo courtesy of Shin-ichiro Imai/Washington University in St. Louis).
The process behind the functioning of a specific protein already believed to play a role in longevity has recently been established to do just that, lengthen lifespan.

Developmental biologist Dr. Shin-ichiro Imai, from Washington University in St. Louis (MO, USA), discovered that instead of delaying the aging process, the protein works in the brain to delay the onset of aging, thus extending youth and adding those energetic years onto one’s life span.

The researchers engineered lab mice that expressed higher than normal levels of Sirt1 in their brain and saw a substantial extension in the animals’ life spans. The scientists specifically found that Sirt1 plays a vital role in protecting against age-related declines in skeletal muscle, physical activity, body temperature, oxygen consumption, and quality of sleep. The start of the disease process in mice trigger to contract cancer was also delayed.

This new finding could help researchers better determine how to extend the life span of other mammals, including humans. The result is published September 3, 2013, in the journal Cell Metabolism.

Related Links:
Washington University in St. Louis


comments powered by Disqus

Channels

Drug Discovery

view channel

Ibuprofen May Restore Immune Function in Older Individuals

New research suggests that macrophages from the lungs of old mice respond differently to infections than those of young mice, and ibuprofen given to the mice reversed these changes. New research using lab mice suggests that the solution to more youthful immune function might already be a common over-the-counter pain reliever.... Read more

Therapeutics

view channel
Image: Hair follicle (blue) being attacked by T cells (green) (Photo courtesy of Christiano Lab/Columbia University Medical Center).

Hair Restoration Method Clones Patients’ Cells to Grow New Hair Follicles

Researchers have developed of a new hair restoration approach that uses a patient’s cells to grow new hair follicles. In addition, the [US] Food and Drugs Administration (FDA) recently approved a new drug... Read more

Lab Technologies

view channel
Image: Leica Microsystems launches the inverted research microscope platform Leica DMi8 (Photo courtesy of Leica Microsystems).

New Inverted Microscope Designed to Readily Adapt to Changing Research Demands

A new inverted microscope for biotech and other life science laboratories was designed to readily accommodate modifications and upgrades to allow it to keep current with changing research demands and interests.... Read more

Business

view channel

Partnership Established to Decode Bowel Disease

23andMe (Mountain View, CA,USA), a personal genetics company, is collaborating with Pfizer, Inc. (New York, NY, USA), in which the companies will seek to enroll 10,000 people with inflammatory bowel disease (IBD) in a research project designed to explore the genetic factors associated with the onset, progression, severity,... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.