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Image: Nanorobotic agents composed of more than 100 million flagellated bacteria - and therefore self-propelled - and loaded with drugs that moved by taking the most direct path between the drug\'s injection point and the area of the body to cure (Photo courtesy of the Montréal Nanorobotics Laboratory, Polytechnique Montréal).

Magnetically Guided Bacteria Transport Drug-Loaded Liposomes to Hypoxic Tumors

A novel transport system for toxic chemotherapeutic drugs is based on a species of bacteria that can be magnetically guided to a tumor where it releases drug-loaded liposomes into the tumor's hypoxic center. More...
24 Aug 2016
Image: An illustration of the Zika virus (Photo courtesy of Getty Images).

Zika Virus Proteins Linked to Fetal Microcephaly through Activation of Autophagy Pathway

Two Zika virus (ZIKV) proteins have been implicated in causing microcephaly by inhibiting a molecular pathway required for normal fetal brain development. More...
24 Aug 2016
Image: Teneema Kuriakose, Ph.D., a postdoctoral research associate, and Thirumala-Devi Kanneganti, Ph.D. Immunologists have identified the protein trigger in the body’s quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death (Photo courtesy of St. Jude Children’s Research Hospital).

Lung Cell Protein Triggers a Dangerous Immune Response

A protein in the cytoplasm of lung cells helps protect against viral infection, but following invasion by the influenza virus, the same protein stimulates the immune system to overact, which can lead to inflammation or pneumonia. More...
23 Aug 2016
Image: Antibacterial drugs cause changes in the intestinal flora. These changes have an influence on the capacity of the liver and kidneys to detoxify and eliminate therapeutic drugs due to large changes in the metabolizing and transport proteins (Photo courtesy of Dr. Sumio Ohtsuki, Kumamoto University).

Antibiotics-Induced Changes to Gut Bacteria Influence Expression of Drug Side Effects

Antibiotic treatment disrupts the normal bacterial population of the gut resulting in changes in how the body deals with the breakdown and transport of drugs and other metabolites, which may increase the impact of deleterious side effects. More...
23 Aug 2016
Image: A representation of the crystal structure of a CRISPR-associated protein (Photo courtesy of Wikimedia Commons).

Genetic Engineers Use CRISPR/Cas9 to Transform Fibroblasts into Neurons

A team of biomedical engineers used precisely controlled CRISPR/Cas9 gene editing to convert mouse embryonic fibroblasts to functional induced neuronal cells. More...
23 Aug 2016
Image: A molecular model showing the experimental antibody drug ZMapp binding to the Ebola virus, here targeting the virus\'s GP protein (Photo courtesy of Dr. Andrew Ward and Dr. Jesper Pallesen, Scripps Research Institute).

High-Resolution Cryo-EM Images Increase Understanding of Anti-Ebola Drug

High-resolution cryo-electron microscopy images have revealed more precise information as to how the experimental drug ZMapp binds to the Ebola virus and provide insights into how the drug prevents growth of the pathogen. More...
18 Aug 2016

Synthetic Antioxidant Peptide Protects Mice from Lethal Levels of Radiation

An antioxidant peptide compound that mimics those produced by the bacterium Deinococcus radiodurans was found to effectively protect cell cultures and mice exposed to lethal levels of gamma radiation. More...
18 Aug 2016

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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