Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH MEDIA
GLOBETECH PUBLISHING LLC
GLOBETECH PUBLISHING LLC

Friendly Bacteria Found in Probiotic Drinks May Shrink Solid Tumors

By BiotechDaily International staff writers
Posted on 15 Apr 2013
Friendly bacteria typically found in probiotic drinks could be used to shrink tumors, according to new research.

Researchers, from the University of Ulster (Northern Ireland) and Sonidel, Ltd. (Dublin, Ireland), examined the effect on tumors of the common Lactobacillus casei, which is found in the gut and human mouth, and a substance used in many probiotic drinks.

When injected directly into tumors, the new findings suggest that L. Casei could suppress tumor growth. Earlier studies suggest that specific kinds of bacteria grow well in solid tumors, which created the potential to use these kinds of bacteria to degrade tumors from the inside out. This study was structured to evaluate the hypothesis using a harmless kind of bacteria—L. Casei was a good candidate.

The researchers cultured the bacteria in beads, inside a growth solution. The research revealed that the bacteria generate molecules that are toxic to tumors. To further assess the hypothesis, the researchers then injected the encapsulated bacteria directly into tumors in lab mice. The bacteria substantially suppressed tumor growth. These research findings suggest that this approach has a potential therapeutic benefit in the treatment of solid tumors.

The study’s findings were published December 2012 in the International Journal of Medical Microbiology.

Related Links:

University of Ulster
Sonidel




Channels

Genomics/Proteomics

view channel
Image: The photo shows a mouse pancreatic islet as seen by light microscopy. Beta cells can be recognized by the green insulin staining. Glucagon is labeled in red and the nuclei in blue (Photo courtesy of Wikimedia Commons).

Regenerative Potential Is a Trait of Mature Tissues, Not an Innate Feature of Newly Born Cells

Diabetes researchers have found that the ability of insulin-producing beta cells to replicate and respond to elevated glucose concentrations is absent in very young animals and does not appear until after weaning.... Read more

Biochemistry

view channel
Image:  Model depiction of a novel cellular mechanism by which regulation of cryptochromes Cry1 and Cry2 enables coordination of a protective transcriptional response to DNA damage caused by genotoxic stress (Photo courtesy of the journal eLife, March 2015, Papp SJ, Huber AL, et al.).

Two Proteins Critical for Circadian Cycles Protect Cells from Mutations

Scientists have discovered that two proteins critical for maintaining healthy day-night cycles also have an unexpected role in DNA repair and protecting cells against genetic mutations that could lead... Read more

Business

view channel

Roche Acquires Signature Diagnostics to Advance Translational Research

Roche (Basel, Switzerland) will advance translational research for next generation sequencing (NGS) diagnostics by leveraging the unique expertise of Signature Diagnostics AG (Potsdam, Germany) in biobanks and development of novel NGS diagnostic assays. Signature Diagnostics is a privately held translational oncology... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.