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Events

12 Apr 2017 - 14 Apr 2017
22 Apr 2017 - 26 Apr 2017

Drug Discovery

Image: Treatment with fusicoccin-A induces the regeneration of damaged axons towards the center of the injury. The axons are stained in green and the tips of the growing axons, called growth cones, are stained in red (Photo courtesy of McGill University).

Drugs Identified May Stimulate Axon Regeneration

A team of neurological science researchers has identified a class of small molecular growth promotors that may prove to be the basis for drugs designed to correct loss of axons following brain or nervous system injury or other disorders and diseases, including multiple sclerosis and neurodegenerative conditions. More...
21 Mar 2017
Image: According to researchers, a rheumatoid arthritis treatment that suppresses the growth of PTEN mutant cancer cells could lead to targeted therapies against aggressive cancers that have few treatment options (Photo courtesy of Shutterstock).

RA Drug Blocks Growth of PTEN-Mutant Cancers

Cancer researchers have found that a drug approved for treatment of rheumatoid arthritis may block the growth of PTEN-mutant tumors by inhibiting the enzyme dihydroorotate dehydrogenase. More...
17 Mar 2017
Image: Researchers say those who have a genetic disposition for storing fat deposits primarily at their waistline are at a higher risk of developing diabetes and coronary heart disease (Photo courtesy of Massachusetts General Hospital).

Body Type Can Increase Risk of Heart Disease and Diabetes

Researchers have identified a pattern of gene variants associated with an “apple-shaped” body type, in which weight is deposited around the abdomen rather than in the hips and thighs, increases risk for type 2 diabetes and coronary heart disease, as well as the incidence of several cardiovascular risk factors. More...
17 Mar 2017
Image: The organ-on-a-chip platform seeks to recapitulate the complex microenvironment of blood vessels using miniaturized microfluidic devices (Photo courtesy of Joao Ribas, Brigham and Women\'s Hospital).

Biomechanical Stress and Inflammation Linked Using Muscle Cells

A team of biomedical engineers used induced pluripotent stem cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) to investigate the relationship between biomechanical stress and inflammation in an organ-on-a-chip device that mimicked the microenvironment of the cardiovascular system. More...
15 Mar 2017
Image: New research suggests clinical trials for new RA drugs should also focus on eliminating the protein antibodies that cause the disease (Photo courtesy of iStock).

Researchers Define Autoantibody-Producing Role of B-Cells in RA

The results of a recently published paper suggest that clinical trials for new rheumatoid arthritis drugs should shift from their sole focus on relieving inflammation to eliminating the B-cells that produce the anti-citrullinated protein antibodies that are the cause of the disease. More...
08 Mar 2017
Image: A ball and stick depiction of a glucose sugar molecule (Photo courtesy of SPL).

Metabolic Glycoengineering Introduces Targets for Guided Drug Treatment

The advanced technique of metabolic glycoengineering was used to insert unusual sugar molecules into the membranes of tumor cells in order to identify the cells for destruction by targeted chemotherapy. More...
03 Mar 2017
Image: Macrophages with ingested nanoparticles (green) (Photo courtesy of the Bourquin Laboratory, University of Geneva).

Assay Determines Suitability of Nanoparticles for In Vivo Use

A team of Swiss researchers has developed a flow cytometry-based test to determine whether specific types of nanoparticles are suitable for use in humans or animals. More...
28 Feb 2017

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The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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