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Drug Discovery

New Computational Tool Designed for Cancer Treatment

Many human tumors express indoleamine 2,3-dioxygenase, an enzyme that mediates an immune-escape in several cancer types. More...
05 Mar 2010

Sceptrin Restricts Cell Motility and May Prevent Tumor Metastasis

Investigators have demonstrated the ability of the natural compound sceptrin to inhibit the motility of cells and suggested a possible future role for this compound as a drug to prevent the metastasis of tumor cells. More...
03 Mar 2010

Gold Nanoparticles Kill Cancer Cells by Stopping Cell Division

Gold nanoparticles that penetrate the nucleus of cancer cells damage the DNA, prevent the cells from completing the process of cell division, and lead to programmed death of the cells. More...
03 Mar 2010

Prototype Drug Blocks Critical Tuberculosis Virulence Factor

A chemical compound has been identified that inhibits the activity of the Mycobacterium tuberculosis protein, tyrosine phosphatase mPTPB, and may be the prototype for a new generation of drugs for the treatment of tuberculosis. More...
02 Mar 2010

Targeted Nanogels Specifically Transport siRNA into Ovarian Cancer Cells

Nanoparticles crafted from hydrogels have been coated with receptor-specific peptides and used to transport siRNA capable of inhibiting the synthesis of epidermal growth factor receptor into ovarian cancer cells. More...
01 Mar 2010

Live Vaccines Protected by a Sugar Glass Film Do Not Require Refrigeration

Researchers have announced the development of a process for preserving living, virus-based vaccines without the need for refrigeration, a major step in providing modern healthcare to countries in the developing world. More...
01 Mar 2010

Drug Discovery Process More Accurate, Less Expensive Using Mass Spectrometry Application

Cancer and cell biology experts have developed a new mass spectrometry-based tool they report provides more precise, cost-effective data collection for drug discovery efforts. More...
25 Feb 2010
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The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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