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Drug Discovery

Oxidized LDL Predicts Response to Interferon Treatment of Chronic Hepatitis C and May Be a Treatment Option

Oxidized low-density lipoprotein in the blood was shown to predict responsiveness to interferon treatment in patients with chronic Hepatitis C virus infection and to inhibit spread of the virus in vitro.  More...
27 May 2015
Image: Molecular model of the anti-cancer drug 5-fluorouracil (Photo courtesy of Wikimedia Commons).

Novel Microcapsule Approach Reduces Toxic Side Effects of Chemotherapy

Cancer researchers have reduced chemotherapy's toxic side effects by using nanoporous capsules to transport an enzyme to the site of a tumor where it is activated by a selective heating process to convert a pro-drug into a toxic anticancer agent.   More...
25 May 2015

Interferon-Lambda Prevents West Nile Virus from Crossing the Blood-brain Barrier

The cytokine interferon-lambda prevents West Nile virus from infecting brain cells by reducing transport of large molecules across the blood-brain barrier.  More...
24 May 2015

Exome Delivery of the Anti-Oxidant Catalase Reduces Parkinson's Disease Symptoms in Mouse Model

The exosome delivery of the antioxidant enzyme catalase was shown to dramatically reduce symptoms of Parkinson's disease in a mouse model.  More...
20 May 2015

Silicon Microparticles Boost Effectives of Potential Breast Cancer Vaccines

Microparticles constructed from porous silicon were found to increase the effectiveness of potential anti-breast-cancer vaccines by stimulating a type I interferon response even when not carrying any specific antigen.  More...
19 May 2015
WATERS CORPORATION

DNA and Protein Composite Vaccine Produces Long Lasting Immunity Against Chagas Disease in Mice

A candidate vaccine for Chagas disease was found to induce long-lasting immunity against the Trypanosoma cruzi parasite in mice.  More...
17 May 2015

Blocking ITK Activity Slows Growth of Malignant Melanoma in Mouse Model

Development of malignant melanoma was found to depend to some extent on the activity of the enzyme produced by the gene interleukin-2 inducible T-cell kinase.  More...
13 May 2015


The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
 

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02 Jun 2015 - 03 Jun 2015
15 Jun 2015 - 18 Jun 2015
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