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Drug Discovery

Disrupted Genetic Systems Discovered in Autistic Brain

By investigating gene collections rather than individual genes, researchers have now identified specific functional systems with genetic disruptions in the autistic brain. More...
17 May 2012

Nanoparticle Technology Rehabilitates Abandoned Anticancer Drugs

Cancer researchers have used nanoparticle technology to reexamine potentially useful anticancer drugs that had failed in clinical trials due to problems of toxicity, stability or solubility. More...
17 May 2012

Loss of Specific MicroRNA Spurs Drug Resistance in Breast Cancer Cells

A study determined that development of resistance to the chemotherapeutic drug tamoxifen by breast tumors was due to the disappearance of a specific microRNA. More...
17 May 2012

Molecular Signaling Network a Promising Drug Target in Many Types of Tumors

Cancer researchers have identified a molecular signaling network present in many types of tumors that they suggest could be a promising target for a new generation of chemotherapeutic drugs. More...
09 May 2012

Spindle Assembly Checkpoint Proteins May Be Targeted by New Anticancer Drugs

Data published on the molecular factors that control chromosome segregation during cell division may help drug developers in their efforts to replace the taxane family of chemotherapeutic agents with similarly effective but less toxic drugs. More...
09 May 2012

Complex Fusion Protein Stabilizes and Targets Therapeutic siRNAs

A recent paper described the development of novel method for delivering targeted doses of therapeutic small interfering RNAs that was successfully tested in a mouse breast-cancer model. More...
03 May 2012

Heart Cells Created in the Lab Devised for Drug Testing, Disease Research

Investigators used induced pluripotent stem cell technology to create heart-muscle-like cells from the skin of patients with dilated cardiomyopathy. More...
02 May 2012
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The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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