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Drug Discovery

Test for P53 Mutations to Aid Biotech Researchers and Drug Developers

A biotech services company in the United Kingdom has launched an in-house service that utilizes a next generation sequencing test to identify mutations in the P53 tumor suppressor gene.  More...
19 Nov 2014

Radiation Oncology Drug Platform Oxygenates Tumors Cells to Make Them More Sensitive to Therapy

A new patent has been issued for photodynamic therapy for tumors with a localized delivery technique, which offers broad protection for new systems and methods for reversing hypoxia in therapy-resistant tumors, and for delivering combination therapy to peripheral tumors, specifically lung cancer.   More...
12 Nov 2014
SLAS - Society for Laboratory Automation and Screening

Omega 3 Found to Improve Behavior in Children with ADHD

Supplements of the fatty acids omega 3 and 6 can help children and adolescents who have a specific kind of have attention deficit hyperactivity disorder. Moreover, these findings indicate that a customized cognitive training program can improve problem behavior in children with ADHD.   More...
03 Nov 2014
Image: Leelamine is a natural compound isolated from pine bark (Photo courtesy of Pennsylvania State College of Medicine).

Nanoparticle-Encapsulated Leelamine Shown Safe for Treating Malignant Melanoma

Cancer researchers have packaged an effective but highly toxic cancer drug into a nano-liposome package that can be delivered to malignant melanoma cells with minimal damage to surrounding normal tissues.  More...
02 Nov 2014
Image: The nano-cocoon drug delivery system is biocompatible, specifically targets cancer cells, can carry a large drug load, and releases the drugs very quickly once inside the cancer cell. Ligands on the surface of the \"cocoon\" trick cancer cells into consuming it. Enzymes (the “worms\" in this image) inside the cocoon are unleashed once inside the cell, destroying the cocoon and releasing anticancer drugs into the cell (Photo courtesy of Dr. Zhen Gu, North Carolina State University).

Novel Anticancer Drug Delivery System Utilizes DNA-Based Nanocapsules

A novel DNA-based drug delivery system minimizes damage to normal tissues by utilizing the acidic microenvironment inside cancer cells to trigger the directed release of the anticancer drug doxorubicin.  More...
26 Oct 2014

New Therapeutic Approach Floods Prostate Cancer Cells with Copper

A novel approach for treating prostate cancer is based on the co-administration of the drug disulfiram and copper, an element that the growing cancer cells require.  More...
26 Oct 2014

Molecule in Green Tea Used as Carrier for Anticancer Proteins

A molecule that is a key ingredient in green tea can be employed as a carrier for anticancer proteins, forming a stable and effective therapeutic nanocomplex. This new discovery could help to construct better drug-delivery systems.  More...
16 Oct 2014

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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