Features | Partner Sites | Information | LinkXpress
Sign In
GLOBETECH MEDIA
GLOBETECH PUBLISHING LLC
GLOBETECH PUBLISHING LLC

European Bioinformatics Sector Expected to Surge

By BiotechDaily International staff writers
Posted on 01 Jun 2014
An intra-European purchase agreement will boost the bioinformatics field by combining an exhaustive genomics data base with a highly intuitive software suite.

Qiagen N.V. (Venlo, The Netherlands) will be expanding its industry-leading portfolio of bioinformatics solutions called "Ingenuity Knowledge Base" by incorporating the genomics analysis and sequencing data that comprises the Biobase (Wolfenbüttel, Germany) HGMD (Human Gene Mutation Database) and PGMD (PharmacoGenomic Mutation Database) databases.

HGMD provides comprehensive data on human inherited disease mutations. Widely used in human genetics research, diagnostics, and personal genomics, HGMD enables quick access to single mutation queries and advanced search applications. PGMD identifies all published gene variants that have been shown to affect drug response in patients, with multiple delivery models for accessing this data, including an intuitive exploratory interface and a data download for in-house analysis systems.

“The ability of next-generation sequencing (NGS) to rapidly deliver genomic insights is opening up new frontiers for clinical research and medicine, and Qiagen is strategically addressing customers’ needs to interpret the massive amounts of data generated by NGS. With HGMD and other content from Biobase, a respected organization with a dedicated team and robust line of unique databases and software, Qiagen is further extending its competitive advantage as the overall market leader for clinical interpretation of human sequencing data,” said Peer M. Schatz, CEO of Qiagen. “Already today, more than 15,000 users worldwide rely on Qiagen’s bioinformatics products for interpretation and have processed over a quarter of a million genome sequences. HGMD is a unique fit with our offering and will integrate well. We expect to drive additional adoption of this leading literature-based knowledge base used by clinical reference labs for annotating hereditary variants, as well as Biobase’ other solutions by having integrated them into interpretation solutions shared with our Ingenuity Knowledge Base, adding value for Qiagen and Biobase customers and accelerating our growth drivers in NGS and bioinformatics.”

When the acquisition has been completed, Biobase will be renamed Qiagen Wolfenbüttel.

Related Links:
Qiagen N.V.
Biobase



Channels

Genomics/Proteomics

view channel
Image: The bone marrow of mice with normal ether lipid production (top) contains more white blood cells than are found in the bone marrow of mice with ether lipid deficiency (bottom) (Photo courtesy of Washington University School of Medicine).

Inactivating Fatty Acid Synthase Reduces Inflammation by Interfering with Neutrophil Membrane Function

The enzyme fatty acid synthase (FAS) was shown to regulate inflammation by sustaining neutrophil viability through modulation of membrane phospholipid composition. Neutrophils are the most abundant... Read more

Drug Discovery

view channel
Image: Researchers have attached two drugs—TRAIL and Dox—onto graphene strips. TRAIL is most effective when delivered to the external membrane of a cancer cell, while Dox is most effective when delivered to the nucleus, so the researchers designed the system to deliver the drugs sequentially, with each drug hitting a cancer cell where it will do the most damage (Photo courtesy of Dr. Zhen Gu, North Carolina State University).

Anticancer Drug Delivery System Utilizes Graphene Strip Transporters

The ongoing search by cancer researchers for targeted drug delivery systems has generated a novel approach that uses graphene strips to transport simultaneously the anticancer agents TRAIL (tumor necrosis... Read more

Biochemistry

view channel

Blocking Enzyme Switch Turns Off Tumor Growth in T-Cell Acute Lymphoblastic Leukemia

Researchers recently reported that blocking the action of an enzyme “switch” needed to activate tumor growth is emerging as a practical strategy for treating T-cell acute lymphoblastic leukemia. An estimated 25% of the 500 US adolescents and young adults diagnosed yearly with this aggressive disease fail to respond to... Read more

Therapeutics

view channel
Image: Cancer cells infected with tumor-targeted oncolytic virus (red). Green indicates alpha-tubulin, a cell skeleton protein. Blue is DNA in the cancer cell nuclei (Photo courtesy of Dr. Rathi Gangeswaran, Bart’s Cancer Institute).

Innovative “Viro-Immunotherapy” Designed to Kill Breast Cancer Cells

A leading scientist has devised a new treatment that employs viruses to kill breast cancer cells. The research could lead to a promising “viro-immunotherapy” for patients with triple-negative breast cancer,... Read more

Lab Technologies

view channel
Image: MIT researchers have designed a microfluidic device that allows them to precisely trap pairs of cells (one red, one green) and observe how they interact over time (Photo courtesy of Burak Dura, MIT).

New Device Designed to See Communication between Immune Cells

The immune system is a complicated network of many different cells working together to defend against invaders. Effectively combating an infection depends on the interactions between these cells.... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.