Features | Partner Sites | Information | LinkXpress
Sign In
BioConferenceLive
GLOBETECH PUBLISHING
JIB

Collaboration to Further Novel Cancer Immunotherapy Approach

By BiotechDaily International staff writers
Posted on 31 Mar 2014
A new immunotherapy program has been established to drastically slash cancer deaths by targeting eight cancers with the support of several new research platforms that provide infrastructure, technology, and know-how.

MedImmune (Gaithersburg, MD, USA), AstraZeneca’s (Cambridge, UK) global biologics research and development arm, has entered into a three-year translational and clinical research collaboration with The University of Texas MD Anderson Cancer Center (Houston, TX, USA) to evaluate therapies that trigger patients’ immune systems to attack their cancers through MD Anderson’s Moon Shots Program.

MedImmune is conducting clinical trials using a new therapeutic concept that targets immune cells to improve their tumor-fighting ability, rather than targeting the tumor cell itself. Through the collaboration, MD Anderson will evaluate several of MedImmune’s immunotherapy molecules in a clinical setting to better determine how these molecules elicit immune response in patients.

The scientists hope that data gathered from these studies will provide new clues on treatment-related changes to tumors, with the ultimate goal of identifying the best combination therapies and developing biomarkers to guide and assess the safety and effectiveness of MedImmune’s immunotherapy molecules.

“We are excited to work with MD Anderson in the Moon Shots program, pairing their unique immunotherapy platform with our innovative portfolio of immune-mediated cancer therapies,” said Dr. Ed Bradley, senior vice president and head of MedImmune’s oncology innovative medicines unit. “Our partnership will provide MedImmune with an invaluable opportunity to evaluate the biological impact of our immune-mediated cancer agents, both as monotherapy and combination therapy.”

“Our collaboration with MedImmune, a leader in the field of immunotherapy, will draw on the strengths of both institutions to push ahead for more effective treatments for cancer patients,” said Jim Allison, PhD, executive director of the moon shots immunotherapy platform and professor and chair of immunology at MD Anderson.

MedImmune is the worldwide biologics research and development arm of AstraZeneca, a global, innovation-driven biopharmaceutical business that focuses on the discovery, development, and commercialization of small molecule and biologic prescription medicines. MedImmune is conducting novel research and exploring pathways across key therapeutic areas, including respiratory, inflammation and autoimmunity; cardiovascular and metabolic disease; oncology; neuroscience; and infection and vaccines.

Related Links:

MedImmune
University of Texas MD Anderson Cancer Center



comments powered by Disqus

Channels

Genomics/Proteomics

view channel
Image: In the liver tissue of obese animals with type II diabetes, unhealthy, fat-filled cells are prolific (small white cells, panel A). After chronic treatment through FGF1 injections, the liver cells successfully lose fat and absorb sugar from the bloodstream (small purple cells, panel B) and more closely resemble cells of normal, non-diabetic animals (Photo courtesy of the Salk Institute for Biological Studies).

Fibroblast Growth Factor 1 Treatment Restores Glucose Control in Mouse Diabetes Model

A "vaccine" based on the metabolic regulator fibroblast growth factor 1 (FGF1) removed the insulin resistance that characterizes type II diabetes and restored the body's natural ability to manage its glucose... Read more

Drug Discovery

view channel
Image: Molecular rendering of the crystal structure of parkin (Photo courtesy of Wikimedia Commons).

Cinnamon Feeding Blocks Development of Parkinson's Disease in Mouse Model

A team of neurological researchers has identified a molecular mechanism by which cinnamon acts to protect neurons from damage caused by Parkinson's disease (PD) in a mouse model of the syndrome.... Read more

Therapeutics

view channel
Image: This type of electronic pacemaker could become obsolete if induction of biological pacemaker cells by gene therapy proves successful (Photo courtesy of Wikimedia Commons).

Gene Therapy Induces Functional Pacemaker Cells in Pig Heart Failure Model

Cardiovascular disease researchers working with a porcine heart failure model have demonstrated the practicality of using gene therapy to replace implanted electronic pacemakers to regulate heartbeat.... Read more

Lab Technologies

view channel

Precise Ion Irradiation Dosing Method Developed for Cancer Therapy

Scientists are employing nuclear physics principles to provide more effective approaches to radiotherapy treatment for cancer patients. Radiation therapy using heavy ions is best suitable for cancer patients with tumors that are difficult to access, such as in the brain. These particles scarcely damage the penetrated... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.