Features Partner Sites Information LinkXpress
Sign In
Demo Company

Major European Research Project to Focus on Detection and Prevention of Rheumatoid Arthritis

By BiotechDaily International staff writers
Posted on 14 Aug 2013
Print article
The European Union has agreed to fund a multimillion euro research project aimed at detection and prevention of rheumatoid arthritis in individuals who do not yet have symptoms of the disease.

Funding for the first four years of the EuroTEAM (Towards Early diagnosis and biomarker validation in Arthritis Management) project will be more than 5.7 million euros. These funds will underwrite the research efforts of 13 academic partners from six European countries - the United Kingdom, the Netherlands, Sweden, Switzerland, Germany, and Austria, as well as three industry partners, from Germany, the Netherlands, and Iceland.

The biotech company ORGENTEC Diagnostika (Mainz, Germany), which will head up the search for biomarkers in the blood, will be a major player on EuroTEAM. ORGENTEC is a global leader in development, production, and marketing of test systems for laboratory diagnostics. The company offers numerous highly specific ELISA tests, immunoblots, and kits for immunofluorescence assays. Its point of care test "rheumachec" was the first rapid test for diagnosing rheumatoid arthritis.

In the case of a chronic inflammatory disease such as rheumatoid arthritis, the goal is prevention. Development of preventive strategies and therapies requires (1) identification of biomarkers that can be used to predict an individual's risk of developing the disease, and (2) identification and characterization of modifiable disease mechanisms that can be manipulated in the early phases of disease.

The key objective of the TEAM consortium is to specifically identify diagnostic biomarkers and disease mechanisms operating during the transition from health to rheumatoid arthritis. The plan is to achieve this by developing a collaborative, integrated program of work that will link academic researchers with key SMEs (small and medium sized enterprises) involved in biomarker development to produce a personalized predictive biomarker profile for patients destined to develop rheumatoid arthritis. Ultimately, the project will directly involve other medical specialists and patients.

Related Links:
ORGENTEC Diagnostika

Print article



view channel
Image: Left: Green actin fibers create architecture of the cell. Right: With cytochalasin D added, actin fibers disband and reform in the nuclei (Photo courtesy of the University of North Carolina).

Actin in the Nucleus Triggers a Process That Directs Stem Cells to Mature into Bone

A team of cell biologists has discovered why treatment of mesenchymal stem cells (MSCs) with the mycotoxin cytochalasin D directs them to mature into bone cells (osteoblasts) rather than into fat cells... Read more


view channel

Molecular Light Shed on “Dark” Cellular Receptors

Scientists have created a new research tool to help find homes for orphan cell-surface receptors, toward better understanding of cell signaling, developing new therapeutics, and determining causes of drug side-effects. The approach may be broadly useful for discovering interactions of orphan receptors with endogenous, naturally... Read more

Lab Technologies

view channel
Image: The new ambr 15 fermentation micro-bioreactor system was designed to enhance microbial strain screening applications (Photo courtesy of Sartorius Stedim Biotech).

New Bioreactor System Streamlines Strain Screening and Culture

Biotechnology laboratories working with bacterial cultures will benefit from a new automated micro bioreactor system that was designed to enhance microbial strain screening processes. The Sartorius... Read more
Copyright © 2000-2015 Globetech Media. All rights reserved.