A unique gas distribution system that allows mass cell culture under atmospheric conditions determined by the system operator has been awarded a patent in the United States.

Cell factories are multilayer cell-culture vessels that provide a large surface area for growing anchorage-dependent cells in a space-saving footprint. The Thermo Scientific (Milford, MA, USA) Nunc Cell Factory System with Active Gassing was designed to ensure that each culture tray in the cell factory would be maintained in a controlled, contamination-free user-specified gas mixture.

Using two standard ports for filling of cells and passage of gases, the cell factory system, which is available in 4, 10, and 40-tray models, provides a closed microenvironment for cell cultures producing therapeutic agents or vaccination products.

“The Thermo Scientific Nunc Cell Factory System was the first to enter the disposable bioreactor market, and it provides many advantages, including easy up-scaling, low risk of contamination, and reduced lifetime operating costs,” said Jill Staggert, product-marketing manager at Thermo Scientific. “We also customize ports and provide pre-assembled tubing configurations to support specific applications, as well as offer a wide range of accessories, including equipment such as shakers, manipulators, incubators, shelf systems, peristaltic pumps, single-use bioreactors, and more. Thermo Fisher is dedicated to being the leader in bioproduction processing by offering a full range of complementary production cell culture products.”

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