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05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017
12 Apr 2017 - 14 Apr 2017


Image: A scanning electron microscopic (SEM) image of the microneedle-array beta-cell patch (Photo courtesy of Dr. Zhen Gu, University of North Carolina).

Microneedle Delivery of Beta-Cells Avoids Host Immune Rejection

A novel skin patch filled with living insulin-secreting beta cells was shown to regulate glucose levels in a mouse diabetes model for up to 10 hours while avoiding adverse immune responses.  More...
28 Mar 2016
Image: The three types of heart cells—cardiomyocytes, endothelial cells, and smooth muscle cells—created from ieCPCs (Photo courtesy of Dr. Yu Zhang, Gladstone Institutes).

Stem Cell Therapy Repairs Damaged Heart Muscle in Mouse Myocardial Infarction Model

Advanced stem cell techniques were used to generate expandable cardiovascular progenitor cells from skin fibroblasts, which could repair damage to the heart muscle caused by myocardial infarction.  More...
13 Mar 2016
Image: Reprogrammed stem cells (green) chase down and kill glioblastoma cells (pink), potentially offering a new and more effective treatment option for a disease that has not had any in more than 30 years (Photo courtesy of the University of North Carolina).

Stem Cell Therapies Improve Survival of Mouse Brain Cancer Model

Two papers have described the use of fibrin-embedded, biologically engineered induced neural and mesenchymal stem cells in tumor-homing cytotoxic stem cell therapy that shows promise as a new approach for treating the incurable brain cancer glioblastoma multiforme.  More...
09 Mar 2016

Failing Hearts Switch Fuels to Continue Generating Energy

A new study provides fresh biochemical insight into heart failure and may eventually lead to new diagnostic and pathology tests as well as therapeutic targets to prevent or slow progression of the disease.   More...
24 Feb 2016
Image: Top row: skeletal muscle without dystrophin. Left to right: skeletal muscle nuclei (blue), skeletal muscle (red), missing dystrophin, overlay of all three images to the left. Bottom row: skeletal muscle with restored dystrophin after application of the CRISPR/Cas9 platform. Left to right: skeletal muscle nuclei (blue), skeletal muscle (red), dystrophin (green), Overlay of all three images to the left. Dystrophin appears yellow in overlay image (Photo courtesy of University of California, Los Angeles).

Gene Editing Technique Repairs Mutation Causing Duchenne Muscular Dystrophy

The CRISPR/Cas9 genome editing technique was used to repair the mutation in the dystrophin gene that causes Duchenne muscular dystrophy in induced human pluripotent stem cells derived from DMD patients.   More...
24 Feb 2016

Expanded Collaboration Agreement Intended to Accelerate Development of Anticancer T-cell Immunotherapeutics

Two British biotechnology companies have expanded their strategic collaboration in order to accelerate development of anticancer therapies based on T-cell immunotherapy.  More...
14 Feb 2016
Image: Schematic diagram of dendrimer structure (Photo courtesy of the University of California, Irvine).

Dendrimer-Transported MicroRNA Shown Effective in Treating Mice with Late-Stage Liver Cancer

Cancer researchers have used nanocarriers called dendrimers to transport a specific tumor growth-inhibiting microRNA to the livers of mice with late-stage liver cancer.  More...
10 Feb 2016

BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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