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Therapeutics

Image: The image on the left shows high-grade aggressive prostate cancer before treatment. The image on the right shows no evidence of cancer after combined gene therapy and radiotherapy (Photo courtesy of the Houston Methodist Hospital).

Combined Gene and Radiation Therapy Induces Long-Term Prostate Cancer Remission

Results of a Phase II clinical trial indicated that an experimental gene therapy approach could successfully induce remission of prostate cancer when it was combined with directed radiation treatment.  More...
22 Dec 2015
Image: A- Labeled stem cells target spinal bone fracture; B- Two spinal bone fractures; C- Complete healing of spinal bone fractures eight weeks post treatment with stem cells and PTH (Photo courtesy of Cedars-Sinai Board of Governors Regenerative Medicine Institute).

Combined Stem Cell and Hormonal Therapy Stimulates Bone Growth and Repair

A novel regimen to promote healing of damaged or broken bones is based on combined stem cell and hormonal treatment.  More...
20 Dec 2015
Image: Colorized scanning electron micrograph (SEM) shows a grouping of methicillin resistant Staphylococcus aureus (MRSA) bacteria magnified 20,000 times (Photo courtesy of the CDC – US Centers for Disease Control and Prevention).

SecA Inhibitors Block Growth of Methicillin-Resistant Staphylococcus aureus

A novel class of low molecular weight compounds has been shown to effectively inhibit the growth of methicillin-resistant Staphylococcus aureus, one of the most serious drug-resistant bacterial pathogens.  More...
15 Dec 2015

When Exercise Is Unhealthy: Study Sheds New Light on Sudden Cardiac Death

Researchers have discovered new aspects, involving a mutated protein, of a not-well-understood mechanism that underlies how sudden heart failure can occur during endurance exercise in patients with arrhythmogenic ventricular cardiomyopathy, which currently has no standardized guidelines for exercise management.  More...
06 Dec 2015
Image: Structure of the protein encoded by the CFTR gene (Photo courtesy of Wikimedia Commons).

Advanced Gene Therapy Cures Cystic Fibrosis in Culture and Mouse Models

Improvements in gene therapy technology enabled restoration of ion channel function in cultures of cells from cystic fibrosis patients and in a CF mouse model.  More...
01 Dec 2015

Molecular Light Shed on “Dark” Cellular Receptors

Scientists have created a new research tool to help find homes for orphan cell-surface receptors, toward better understanding of cell signaling, developing new therapeutics, and determining causes of drug side-effects.  More...
24 Nov 2015

Novel Gene Therapy Treatment Extends Life of Mice Severely Affected by Muscular Dystrophy

An alternative gene therapy approach was used to successfully treat a mouse model of Duchenne muscular dystrophy.  More...
11 Oct 2015


BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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