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Laser-Heated Plasmonic Nanoparticles Safely Cause Localized Tumor Destruction

Cancer therapy based on plasmonic nanoparticles that homed to tumors, warmed on exposure to laser irradiation, and then selectively killed the cancer cells was optimized and shown to be effective in a mouse xenograft model. More...
16 Aug 2016

Monoclonal Antibody Treatment Blocks Lymphoma Progression in Mouse Model

Immunotherapy based on monoclonal antibodies that specifically bind to the surface protein junctional adhesion molecule (JAM)-C, which is expressed by a variety of different cell types, including human B lymphocytes and some B-cell lymphoma subtypes, blocked progression of lymphoma in a mouse xenograft model of mantle cell lymphoma. More...
16 Aug 2016

Smart Nanoparticles Deliver Selective Heating to Kill Tumors

Cancer researchers have demonstrated a novel type of "smart" nanoparticle that can destroy a tumor through selective heating while causing minimal damage to surrounding normal tissues. More...
28 Jul 2016

Practice Guidelines Published for Aspergillosis Diagnosis and Management

The guidelines-update focuses on earaly diagnosis and new treatments for patients with of the major forms of aspergillosis: allergic, chronic, and invasive, the latter of which kills 40-80% of those with widespread infection. Early diagnosis of invasive aspergillosis remains critical for more effective treatment. More...
25 Jul 2016

Common Circulating Cell Clusters in Cancer Patients Characterized Anew

In a study of blood samples from colorectal cancer patients, researchers have now discovered the source of these cells and that they are not malignant, potentially opening up a new path to detect and inhibit the spread of cancer. More...
25 Jul 2016

Alpha-1-Antitrypsin Gene Replacement Therapy Cures Emphysema in Mouse Model

A virus-like vector loaded with the gene for production of the enzyme alpha-1-antitrypsin (AAT) successfully established production of the protein in the lungs of mice serving as a model for human emphysema. More...
19 Jul 2016

Blocking Formation of Scar Tissue Increases Susceptibility of Pancreatic Cancer to Immunotherapy

Cancer researchers have shown that treatment with a focal adhesion kinase (FAK) inhibitor rendered pancreatic cancer tumors susceptible to immunotherapy in a mouse model of the disease. More...
13 Jul 2016

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