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Events

06 Jun 2016 - 09 Jun 2016
22 Jun 2016 - 24 Jun 2016
04 Jul 2016 - 06 Jul 2016

Therapeutics

Study Improves Understanding of E. coli H30 Epidemiology, Persistent Infections Remains Unexplained

Researchers have identified populations more vulnerable to infection with pandemic E. coli strain H30, however improved testing is needed to monitor patients due to the high rate of treatment failure. Antibiotic resistance and weakened immunity only partially explain persistent infection. More...
05 May 2016

New Approach Improves Identification of Women at High Risk of Preeclampsia

A new meta-analysis examining 92 cohort studies involving over 25 million pregnancies has provided an unprecedented understanding of risk factors for preeclampsia—some risk factors being strong enough to warrant that a pregnant woman starts on prophylactic treatment with acetylsalicylic acid (ASA) when she has only one. More...
05 May 2016

Stem Cells Derived from Older Individuals May Carry Unsafe Mitochondrial DNA Mutations

Induced pluripotent stem cells (iPSCs) derived from the skin fibroblasts of older individuals have a likelihood of harboring mitochondrial DNA mutations, which may render them unfit for clinical applications. More...
29 Apr 2016

Newly Developed Drug Demonstrates Potent, Selective Activity Against Trypanosomatid Parasites

Using a plant-based compound, scientists have developed a semi-synthetic drug that, upon testing on infected mammalian cells in culture, showed highly effective activity against two parasites from the trypanosomatid family: Leishmania donovani, a cause of visceral leishmaniasis, and Trypanosoma cruzi, cause of Chagas disease.  More...
06 Apr 2016

Link Found Between Brain Metabolism and Fluid Intelligence

By measuring a metabolic activity marker using magnetic resonance spectroscopy, a new study in young adults has indicated that healthy brain metabolism corresponds with fluid intelligence, a measure of one’s ability to solve unusual or complex problems.  More...
03 Apr 2016
Image: Schematic representation of implant for passive immunization by long-term therapeutic antibody delivery. Cells genetically engineered to produce a therapeutic antibody are confined in a macroencapsulation “flat sheet” device and implanted in the subcutaneous tissue for in vivo antibody secretion into the bloodstream. Antibodies reaching the brain target, clear, and prevent the harmful amyloid-beta protein plaques of Alzheimer’s disease (Photo courtesy of Lathuilière A et al, 2016, and Swiss Federal Institute of Technology in Lausanne).

Medical Implant Device Reduces Alzheimer’s Pathology and Provides Passive Immunization

In landmark proof-of-concept study with mice, a cutting-edge subcutaneous-implant capsule developed for treatment for Alzheimer’s disease, successfully directed the immune system against the disease.  More...
03 Apr 2016
Image: A scanning electron microscopic (SEM) image of the microneedle-array beta-cell patch (Photo courtesy of Dr. Zhen Gu, University of North Carolina).

Microneedle Delivery of Beta-Cells Avoids Host Immune Rejection

A novel skin patch filled with living insulin-secreting beta cells was shown to regulate glucose levels in a mouse diabetes model for up to 10 hours while avoiding adverse immune responses.  More...
28 Mar 2016


BioResearch Therapeutics channel deals with all aspects of therapies beyond the five-year horizon.
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