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Biochemistry

Image: Two Anaplasma phagocytophilum bacteria (arrows) bound to host cell surfaces; the bacterium on the right (thick arrow) is invading upon triggering its own uptake. (Photo courtesy of Jason Carlyon, PhD, and Matthew J. Troese, PhD / VCU.)

Molecular Pair Identified as Key to Host-Cell Invasion by Tick-Transmitted Pathogen

A pathogen-host “key and door” molecular pair has been identified as critical for the cell-cell adhesion required for invasion by the tick-transmitted pathogen Anaplasma phagocytophilum. More...
22 Oct 2012

Metabolic Pathway Discovered Has Implications for Diabetes, Obesity, Cancer Therapy

A newly discovered hedgehog-signaling pathway has been found to be a primary regulator of cellular energy metabolism and to include insulin-independent glucose uptake. More...
18 Oct 2012
Image: 2012 Chemistry Nobel laureate Prof. Robert J. Lefkowitz (Photo courtesy of the American Society for Pharmacology and Experimental Therapeutics).

Nobel Prize Awarded for Fundamental Discoveries About G-protein-Coupled Receptors and Cellular Signaling

The 2012 Nobel Prize for Chemistry jointly awarded to scientists Robert J. Lefkowitz and Brian K. Kobilka recognizes the discovery of G-protein-coupled receptors and fundamental discoveries about their molecular structure, functional roles, and signaling mechanisms. More...
16 Oct 2012

Prospective Antidementia Drug Improves Brain Function

A new antidementia drug candidate has been found to be highly active in creating new neuronal connections and improving the cognitive function of rats with Alzheimer’s-like mental impairment. More...
15 Oct 2012

Blood Group O Found to Be Most Susceptible to Cholera

The probability of becoming seriously ill from cholera depends on one’s blood group. Recent research showed that it is possible to find a new treatment for this troublesome illness by studying the molecular structure in the toxin in the cholera bacteria. More...
18 Sep 2012

Soil Bacteria and Human Pathogens Share Multiple Antibiotic Resistance Genes

Researchers have used a high-throughput functional metagenomic approach to show that bacteria in the soil have swapped antibiotic-resistance genes with bacteria that cause disease in humans. More...
12 Sep 2012
Image: The mitotic spindle (microtubules in red, DNA in blue) and the centrosomes (in yellow). (Photo courtesy of Dr. S. Sdelci, IRB Barcelona).

Decisive Role in Cell Division Identified for Centrosomal Protein

The answer to an elusive question about signaling in chromosome distribution and separation has been provided by the discovery of a key role for a centrosomal protein kinase. More...
30 Aug 2012


The Biochemistry channel of BioResearch covers the chemical process of biomolecules and biochemical processes from enzyme-catalyzed reactions to signal transduction, from the biochemistry of cell metabolism down to cell-membrane transport.
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