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Drug Discovery

Image: MRSA (in yellow) is vulnerable to a new polymer-antibiotic combination (Photo courtesy of the [US] National Institute of Allergy and Infectious Diseases).

Metallopolymers Protect Penicillin-Like Antibiotics from Bacterial Beta-Lactamase

Novel drug combinations that unite classical penicillin-like antibiotics with metallopolymers effectively kill bacteria, including "superbugs" such as MRSA that had developed beta-lactamase enzyme-based resistance to the antibiotics.  More...
12 May 2014
Image: Ultrastructural appearance of a single measles virus particle as revealed by thin-section transmission electron microscopy (TEM). It is 100–200 nm in diameter, with a core of single-stranded RNA, and is closely related to the rinderpest and canine distemper viruses (Photo courtesy of the CDC - [US] Centers for Disease Control and Prevention).

Experimental Drug Protects Animal Model from Measles-Like Virus

Working with an animal model that mimics measles in humans, a team of molecular virologists have verified that a novel antiviral drug may complement the currently used vaccine and lead to eradication of the disease.  More...
04 May 2014
SLAS - Society for Laboratory Automation and Screening

Vitamin D May Raise Survival Rates Among Cancer Patients

Cancer patients who have higher levels of vitamin D when they are diagnosed are inclined to have better survival rates and remain in remission longer than patients who are vitamin D-deficient, according to new research.  More...
04 May 2014
Image: Cultured bacteria showing increased sensitivity to antibiotics with the additional of a metallopolymer (Photo courtesy of University of South Carolina).

New Approach Restores Effectiveness of Older Antibiotics

Methicillin-resistant Staphylococcus aureus, a complex of multidrug-resistant Gram-positive bacterial strains, has proven especially problematic in both hospital and community settings.  More...
29 Apr 2014

NMR Spectroscopy Nature Bank Creates Limitless Opportunities for Drug Discovery

Australian researchers have developed a new tool for finding natural compounds that could form the foundation of innovative therapeutic agents.  More...
28 Apr 2014

Retinoic Acid Prevents Precancerous Breast Cells from Progressing to Full-Blown Cancer

Retinoic acid, a derivative of vitamin A, was found to prevent pre-cancerous breast cells from progressing to full-blown cancer but did not have any effect on breast tumor cells.  More...
20 Apr 2014

Novel Apparatus Mimics the Human Digestive System for Oral Drug Studies

A team of British drug developers has created an instrument that mimics the human digestive system, which will allow them to accurately determine how orally-administered medications are dissolved and then absorbed.  More...
15 Apr 2014

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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