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Drug Discovery

European Biopharmaceutical Companies Launch Anticancer Drug Project

Two European biopharmaceutical companies are joining forces in an intensive effort to develop a new series of anticancer drugs.  More...
12 Nov 2013

New Diabetes Drug Fights Obesity While Controlling Glucose Metabolism

A synthetic peptide that targets receptors for the naturally occurring incretin hormones GLP-1 and GIP is being developed into a drug for the management of diseases associated with impaired glucose tolerance.  More...
11 Nov 2013

Increased Mitochondrial Superoxide Levels Diminish Symptoms of Diabetic Kidney Disease

In vivo studies carried out with chronically diabetic mice have demonstrated a sharp reduction in the production of superoxide anion in the kidney and have shown that restoration of superoxide production reversed most diabetes symptoms.  More...
04 Nov 2013
Image: Scanning electron microscope image of A. baumannii, with maps of its genome (outer circle) and alien-island sequences (inner circle, red) (Photo courtesy of J. Carr, [US] Centers for Disease Control; T. Gianoulis and D. Massa, Yale University).

Synthetic DNA/RNA Analogues Display Potent Antibiotic Activity

Peptide-conjugated phosphorodiamidate morpholino oligomers, which are synthetic DNA/RNA analogues that silence expression of specific genes, were found to inhibit the growth of Acinetobacter in vitro and in vivo.  More...
29 Oct 2013

Histone Deacetylase Inhibitors Boost Parvovirus Cancer Killing Action

The anticancer action of parvoviruses can be dramatically improved by co-treating cancer cells with parvovirus and histone deacetylase inhibitors such as valproic acid.  More...
28 Oct 2013

Vegetable Compound Found to Protect Against Radiation

Researchers have reported that a compound found in cruciferous vegetable such as cauliflower, cabbage, and broccoli shields rats and mice from lethal doses of radiation.   More...
28 Oct 2013

New Drugs Block Synthesis of Metabolites by Nutrient-Challenged Bacteria

 Researchers have developed a new generation of antibiotics that kill bacteria by preventing them from making critical metabolites such as vitamins and amino acids. More...
24 Oct 2013

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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