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Drug Discovery

Collaboration for Radiotherapy Microphere Drug Development for the Treatment of Primary and Secondary Liver Cancer

Sirtex Medical  and Guerbet are entering into a clinical studies collaboration in primary and secondary liver cancer.   More...
31 Mar 2014

New High Precision Kits Available for Gyros Immunoassay Platform

New ready-to-use kits designed for the Gyros high-throughput immunoassay platform will enable generation of high quality data for clinical research and drug development faster than typical ELISA kits.   More...
31 Mar 2014

Cathepsin B Inhibitors Ease Alzheimer's Symptoms by Blocking Amyloid Plaque Formation

Neurobiologists studying the molecular processes underlying Alzheimer's disease have identified the mechanism that explains how inhibition of cathepsin B activity blocks formation of the toxic amyloid-beta peptides that characterize the disease.  More...
27 Mar 2014

Metastasis Drug Target Identified

Cancer researchers have identified a protein that is critically linked to processes leading to metastasis, the deadly spread of cancer away from the primary tumor.  More...
26 Mar 2014
Image: The structure of the ATP-triggered nanoparticle (left) and how the nanoparticles shrink a tumor (right) (Photo courtesy of North Carolina State University).

ATP-Triggered Nanoparticles Effectively Kill Breast Cancer Cells in Mouse Model

A recent paper describes novel nanoparticles that transport toxic anticancer drugs specifically to tumor cells where they are engulfed and induced to release their cargo by the high intracellular concentration of adenosine-5'-triphosphate.  More...
25 Mar 2014
Image: Electron micrograph reveals the morphologic traits of the respiratory syncytial virus (RSV). The virion is variable in shape, and size (average diameter of between 120–300 nm). RSV is the most common cause of bronchiolitis and pneumonia among infants and children under one year of age (Photo courtesy of the CDC - [US] Centers for Disease Control and Prevention).

Human Cell Line Produces High-Quality RSV for Vaccine Production

Cooperation between German and American biotechnology companies may pave the way for development of a vaccine to prevent RSV respiratory infections, which have been estimated to cause nearly 7% of the deaths of infants that die during their first year of life.  More...
23 Mar 2014

Vitamin D Increases Survival of Breast Cancer Patients

Breast cancer patients with high levels of vitamin D in their blood have been found to be twice as likely to survive the disease as women with low levels of this nutrient, according to new research.  More...
23 Mar 2014

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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