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06 Jun 2016 - 09 Jun 2016
22 Jun 2016 - 24 Jun 2016
04 Jul 2016 - 06 Jul 2016

Drug Discovery

Blocking a Long Noncoding RNA Reduces Stroke Damage in Rat Model

By preventing expression of a long noncoding RNA following induced stroke in a rat model, neurosciences researchers were able to limit damage to the brain and reduce the severity of post-stroke symptoms.  More...
29 Dec 2015

Structure of Bacterial Polysaccharide Synthesizing Enzyme May Lead to New Drugs

A team of molecular microbiologists has determined the mode of action of a bacterial enzyme that is critical to the formation of the organism's protective capsular polysaccharide.  More...
28 Dec 2015

FDA-Approved Medications with Antibiotic Activity

From a new study, a number of drugs approved by the US Federal Drug Administraion to treat cancers, parasitic infections, infertility, or other conditions have been found also to have antibiotic properties.  More...
27 Dec 2015
Image: Gram-stained Bacillus subtilis bacteria (Photo courtesy of Wikimedia Commons).

Bacterial Cytological Profiling Streamlines Search for New Antibiotics

Bacterial cytological profiling is a rapid screening technique for identifying and characterizing new antibiotic compounds from mixtures of natural products. More...
22 Dec 2015
Image: Ball-and-stick model of the docetaxel molecule (Photo courtesy of Wikimedia Commons).

Nanoparticle-Delivered Drug Cocktail Blocks Spread of Malignant Melanoma Through the Lymph System

A nanoparticle-based delivery system was used to transport a cocktail of three anticancer drugs to the lymph nodes, which prevented the spread of malignant melanoma in two mouse models.  More...
21 Dec 2015
Image: Colorized scanning electron micrograph (SEM) of the ultrastructural details seen in the cell wall configuration of a number of Gram-positive Mycobacterium tuberculosis bacteria (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Drugs That Block Sulfur Metabolism Show Potential for Treating Latent Tuberculosis

Drugs that target sulfur metabolism have been found to have potential for treating latent tuberculosis infections, including those caused by drug-resistant forms of the bacteria.  More...
14 Dec 2015

Biodegradable Metallic Nanodrops for Safe Cancer Drug Delivery

A novel drug delivery system based on liquid metal nanodrops was used to safely transport the highly toxic chemotherapeutic agent doxorubicin into the cancer cells comprising ovarian tumors in a mouse xenograft model.  More...
14 Dec 2015

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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