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06 Jun 2016 - 09 Jun 2016
22 Jun 2016 - 24 Jun 2016
04 Jul 2016 - 06 Jul 2016

Drug Discovery

LDL-DHA Nanoparticles Selectively Eradicate Liver Tumors in Rat Model System

Uptake of low-density lipoprotein particles loaded with the omega-3 fatty acid docosahexaenoic acid by liver cancer cells resulted in destruction of established tumors in a rat liver cancer model.  More...
22 Feb 2016

Molecular Signals from Neighboring Dendritic Cells Drive Leukemia Growth

Noncancerous cells in the immediate tumor microenvironment supply signals that drive T-cell acute lymphoblastic leukemia growth, and may become attractive therapeutic targets to control the disease.   More...
22 Feb 2016
Image: A neem tree – Azadirachta indica (Photo courtesy of Wikimedia Commons).

Neem Tree Extract Halts Pancreatic Cancer Growth in Mouse Models

Nimbolide, a compound extracted from the leaves of the neem tree  - Azadirachta indica, was shown in culture and mouse models to have potential as a chemotherapeutic agent for the treatment of pancreatic cancer.  More...
21 Feb 2016

Reducing NF-KappaB Signaling Ameliorates Neurological Symptoms in Rett Syndrome Mouse Model

By tracing the molecular pathway linked to the neurological disorder Rett syndrome, researchers have identified molecular pathway that seems to be a potential drug target for alleviating symptoms of the condition.  More...
21 Feb 2016

Innovative DNA Technology May Provide More Efficient Disease Detection and Treatment

Researchers have developed a novel DNA aptamer with potential to improve detection and targeted treatment of infectious diseases and other illnesses, such as cancer.  More...
17 Feb 2016

Lack of Cystine Kills Renal Cancer Cells in Mouse Model

Restricting access to a specific extracellular nutrient—the amino acid cysteine—caused the death of certain types of renal cancer cells both in culture and in a kidney cancer mouse model.  More...
16 Feb 2016

Viral Protein Coat-Based Nanoparticle Delivery System Targets Breast Cancer Cells

A novel transport system for targeted delivery of toxic chemotherapeutic agents or labile protein-based vaccines was based on nanoparticles fashioned from empty hepatitis E virus capsids.  More...
15 Feb 2016

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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