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12 Apr 2017 - 14 Apr 2017
22 Apr 2017 - 26 Apr 2017
New products on world’s medical product marketplace:

Drug Discovery

Image: A flexible polymer patch, which improves the conduction of electrical impulses across damaged heart tissue in animals, can be attached to the heart without the need for stitches (Photo courtesy of the University of New South Wales).

Novel Biocompatible Patch Repairs Heart Damage in Rat Model

A team of Australian and British bioengineers has developed an electrically active biocompatible insert that can repair damage to electro-responsive tissues, such as the brain, heart, and nervous system without need of sutures. More...
13 Dec 2016
Image: An artist’s rendering that depicts troublesome antibodies (purple Ys) attacking conventional PEGylated drugs while ignoring the modified version (Photo courtesy of Stacey Qi, Duke University).

Next-Generation Drugs Circumvent Adverse Immune Response

Drugs conjugated with a modified type of polyethylene glycol (PEG)-based polymer demonstrate enhanced and longer life performance without triggering an immune response from indigenous anti-PEG antibodies. More...
13 Dec 2016
Image: A diagram of thrombin-responsive patch that releases heparin in response to thrombin (Photo courtesy of Yuqi Zhang).

Novel Smart Patch Prevents Fatal Blood Clots in Mouse Model

Tests on a mouse model of thrombosis showed that a novel "smart patch" heparin delivery system prevented clotting efficiently in a feedback-controlled manner. More...
09 Dec 2016
Image: A C10 antibody (purple) interacting with the Zika virus coat (green) (Photo courtesy of Victor Kostyuchenko, Duke-NUS Medical School).

Antibody-Zika Virus Interaction Visualized by Cryo-Electron Microscopy

An international team of molecular virologists used advanced cryo-electron microscopy (cryoEM) techniques to visualize how the potent anti-Zika virus antibody C10 acts to prevent the virus from infecting human cells. More...
07 Dec 2016
Image: A fibroblast undergoing ferroptosis (Photo courtesy of Helmholtz Zentrum München).

Blocking the Acsl14 Enzyme Prevents Ferroptosis-Linked Cell Death

Inhibiting the enzyme Acsl4 (acyl-CoA synthetase long-chain family member 4), which is involved in fatty acid metabolism, has been postulated to be a viable therapeutic approach to preventing ferroptosis-related diseases. More...
25 Nov 2016
Image: The DNA barcode library (Photo courtesy of Shutterstock).

DNA-barcode Labeled Nanoparticles Trace Drug Susceptibility

Novel DNA-barcoded nanoparticles loaded with anti-cancer drugs were used to screen for susceptibility at the cellular level as a first step in the development of personalized cancer therapy. More...
23 Nov 2016
Image: Photomicrographs of fibroblasts from patients with Huntington\'s disease marked with fluorescence. Top row: the cells have accumulated mutant RNA. Bottom row: the cells no longer show blocked RNA accumulations (Photo courtesy of the Center for Genomic Regulation).

Blocking Mutant RNA Cures Huntington's Disease in Mouse Model

Researchers seeking ways to treat Huntington's disease have suggested going after the messenger RNA that mediates between the mutant gene that causes the disease and the toxic protein that causes the neurological damage that characterizes it. More...
23 Nov 2016

Product Showcase

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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