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Drug Discovery

Image: Disruption and removal of malaria parasites by the experimental drug (+)-SJ733 (Photo courtesy of the University of California, San Francisco).

Experimental Antimalaria Drug Induces the Immune System to Destroy Infected Red Blood Cells

An experimental drug for the treatment of malaria was found to induce morphological changes in infected erythrocytes that enabled the immune system to recognize and eliminate them.  More...
14 Dec 2014

New Findings May Lead to Enhanced Treatments for Multiple Sclerosis and Autoimmune Inflammation

A multidisciplinary research team of scientists from Singapore has made a breakthrough discovery of a new type of immune cells that may help in the development of a future treatment for multiple sclerosis.  More...
10 Dec 2014

Scientists Unwind More Mysteries of the Cellular Clock

A new study surveying circadian gene expression provides a new understanding of how one clock leads to at least 8 different subclocks, and may suggest a new venue for drug treatment of clock-based metabolic disorders.  More...
08 Dec 2014

Antiangiogenic Treatment Improves Survival of Mice Models of Ovarian Cancer

A new antiangiogenic treatment with 3TSR has been shown to shrink tumors and improves effectiveness of chemotherapy.  More...
08 Dec 2014

Blocking the Thromboxane Receptor Prevents Alzheimer's Disease in Mouse Model

A recent study carried out on a transgenic mouse model of Alzheimer's disease identified the thromboxane receptor as an active contributor to the development of the disease and a feasible target for drugs to treat it.  More...
30 Nov 2014

Electron Microscope Imaging Shows How Experimental Anti-Ebola Drug Works

Electron microscope imaging has revealed how the experimental drug ZMapp binds to the Ebolavirus and provides insights into how the drug prevents growth of the pathogen.  More...
26 Nov 2014

Activating the Innate Immune System Cures Rotavirus Infection in Mouse Model

Stimulation of the innate immune system, either indirectly with bacterial flagellin or directly with interleukins IL-18 and IL-22, cured Rotavirus infection in a mouse model of the disease.  More...
24 Nov 2014


The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
 
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