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Drug Discovery

Image: Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells (Photo courtesy of the University of Texas, Austin).

Experimental Drug Kills Cancer Cells by Interfering with Their Ion Transport Mechanism

An experimental anticancer drug induces cells to enter a molecular pathway leading to apoptosis by skewing their ion transport systems to greatly favor the influx of chloride anions.  More...
26 Aug 2014

New Drug Triggers Liver Regeneration After Surgery

Investigators have revealed that an innovative complement inhibitor decreases complement-mediated liver cell death, and actually stimulates postsurgery liver regrowth in mice.  More...
25 Aug 2014

Novel Antibody Obliterates Plaque Psoriasis

New studies show that treatment of longstanding plaque psoriasis with secukinumab, a fully human anti-interleukin-17A monoclonal antibody, was associated with rapid and dramatic improvements.  More...
24 Aug 2014

Surface Protein Protects Brain Tumor Cells from Immune Attack

Malignant glioma brain tumor cells suppress the natural killer cell immune response by over expressing the surface protein galectin-1, and suppression of this protein renders the tumor cells susceptible to destruction by the immune system.   More...
19 Aug 2014
Image: The European Commission has approved the use of Avastin combined with chemotherapy as a treatment for women with recurrent ovarian cancer (Photo courtesy of Genentech).

Drug for Treatment of Platinum Resistant Recurrent Ovarian Cancer Approved for Use in Europe

For the first time in more than 15 years the European Commission has approved a new therapeutic option for the most difficult to treat form of ovarian cancer.  More...
18 Aug 2014

Naturally Derived Plant Compounds Protect Skin during Cancer Radiotherapy

Plant-derived natural compounds may provide protection to the skin from the damaging effects of gamma radiation during cancer radiotherapy, according to new research.  More...
06 Aug 2014

New Drug Shown to Be Effective Against Malaria Using Synchrotron Light

 Spanish and Scottish investigators have shown that a new drug is an effective option in the battle against malaria.  More...
04 Aug 2014

The Drug Discovery channel in BioResearch informs about the biotechnology of drug discovery and design from traditional to translational pharma within the five-year horizon.
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