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10 Oct 2016 - 12 Oct 2016
12 Nov 2016 - 16 Nov 2016


Image: Pancreatic tumors are surrounded by a protective \"nest\" made of fibrotic scar tissue and the cells that manufacture it (red). A new study in mice demonstrates that disrupting this fibrous tissue makes immune therapy and chemotherapy more effective in attacking tumors of the pancreas (Photo courtesy of the DeNardo Laboratory, Washington University School of Medicine).

Blocking Formation of Scar Tissue Increases Susceptibility of Pancreatic Cancer to Immunotherapy

Cancer researchers have shown that treatment with a focal adhesion kinase (FAK) inhibitor rendered pancreatic cancer tumors susceptible to immunotherapy in a mouse model of the disease. More...
13 Jul 2016
Image: Skeletal myotubes grown for three weeks on gelatin hydrogel (Photo courtesy of the McCain Laboratory, University of Southern California).

Micromolded Gelatin Scaffolds for Extended In Vitro Culture of Muscle Tissue

A novel in vitro method for growing muscle tissue for an extended period of time depends on minute scaffolds constructed from gelatin. More...
13 Jul 2016
Image: A photomicrograph of a thin section from an ovarian carcinoma (Photo courtesy of Wikimedia Commons).

Combining Genomics and Proteomics Yields Insights into Growth of Ovarian Cancer

Cancer researchers have combined genomic and proteomic data in order to better understand the factors that drive the growth and spread of ovarian cancer. More...
12 Jul 2016
Image: A micrograph of non-alcoholic fatty liver disease (NAFLD). The liver has a prominent macrovesicular steatosis (white/clear round/oval spaces) and mild fibrosis (green). The hepatocytes stain red. Macrovesicular steatosis is lipid accumulation that is so large it distorts the cell\'s nucleus (Photo courtesy of Wikimedia Commons).

Stem Cell-Based Model System to Boost Research on Nonalcoholic Fatty Liver Disease

A team of German liver disease researchers created an in vitro model of nonalcoholic fatty liver disease (NAFLD) using induced pluripotent stem cells that had been differentiated into hepatocyte-like cells. More...
12 Jul 2016
Image: A scanning electron microscope (SEM) micrograph of prostate cancer cells (green) growing in a superporous cryogel with tissue-like elasticity (Photo courtesy of Dr. Bettina Göppert, Karlsruhe Institute of Technology).

In Vitro Three-Dimensional Culture System Enhances Prostate Cancer Cell Growth

A team of cancer researchers developed a three-dimensional in vitro culture system for growing prostate cancer cells in an environment that closely mimics the in vivo tumor microenvironment. More...
07 Jul 2016
Image: Left: a normal mouse muscle mitochondrion. Right: a mitochondrion in mitofusin 2-deficient muscle (Photo courtesy of Dr. D. Sebastian, Institute for Research in Biomedicine, Barcelona).

Loss of Mitochondrial Fusion Enzyme Linked to Age-Related Loss of Muscle Mass

The enzyme mitofusin 2 (Mfn2) was shown to play a key role in the control of age-related muscle mitochondrial damage. More...
06 Jul 2016
Image: HIV-1 viral cores (red) accumulate around the cell nucleus (blue) but remain unable to enter following depletion of the motor protein KIF5B (Photo courtesy of Loyola University Chicago).

HIV Relies on Host Proteins to Clear the Way to the Nucleus

The ability of HIV to transit the cytoplasm and enter the nucleus of an infected cell was found to depend on the combined activities of two host proteins, the Kinesin-1 motor protein, KIF5B, and the nuclear pore component Nup358. More...
06 Jul 2016

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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