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12 Nov 2016 - 16 Nov 2016
16 Nov 2016 - 19 Nov 2016


Image: A photomicrograph of lung tissue infected by pneumonia bacteria (Photo courtesy of Alexandra Bettina, University of Virginia).

Cytokine Required by Immune Cells in Lungs to Defend Against Pneumonia Infection

The cytokine macrophage-colony stimulating factor (M-CSF) was been found to play a critical role in the ability of immune cells in the lung to defend against infection by pneumonia-causing bacteria. More...
09 Aug 2016
Image: The flash-drive-sized device contains two layers of human cells that model the interface between mother and fetus. Microfluidic channels on either side of those layers allow studies of how molecules are transported through, or are blocked by, that interface (Photo courtesy of the University of Pennsylvania).

Organ-on-a-Chip Device Mimics Structure and Function of Human Placental Barrier

A novel lab-on-a-chip device mimics the structure and function of the human placental barrier and allows researchers to carry out in vitro studies on factors influencing fetal development. More...
09 Aug 2016
Image: From left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning due to HGPS that were rebooted by the embryonic stem cell gene NANOG (Photo courtesy of Stelios Andreadis, University at Buffalo).

Expression of Stem Cell Gene Restores Contractile Function to Aged Muscle Cells

Transplanting a stem cell gene into aged muscle cells reversed many indicators of cellular senescence and completely restored the cells' ability to generate contractile force. More...
08 Aug 2016
Image: A diagram of the RNA-binding region of Rbfox2, shown in grey, attached to part of its natural RNA target, depicted in orange, green, blue, and red (Photo courtesy of Yu Chen, Fan Yang and Gabriele Varani, University of Washington).

Novel Method Described for Blocking Action of Cancer-Promoting MicroRNA

A team of molecular biologists has described a novel method for selectively blocking the activity of a cancer-promoting microRNA. More...
08 Aug 2016
Image: In this photomicrograph, the color orange indicates where tau protein has traveled from one neuron to another (Photo courtesy of Dr. Karen E. Duff, Columbia University Medical Center).

Increased Neuronal Activity Stimulates Spread of Tau Proteins in the Brain

Neurodegenerative disease researchers have found that tau proteins released from donor neurons can transfer to recipient cells via the medium, suggesting that at least one mechanism by which tau can transfer in the brain is via the extracellular space. More...
04 Aug 2016
Image: This figure shows confocal images of cells, shown in green, and the corresponding uptake of lipoproteins in those cells, shown in red. Compared to cells with the wild type (WT) form of TREM2, cells with mutant forms of TREM2 (mutant forms Y38C, R47H, R62H, etc.) take up less lipoproteins (Photo courtesy of Dr. Felix Yeh, Genetech).

Defective Lipoprotein Binding in the Brain Linked to Alzheimer's Disease Risk

Mutations in the TREM2 (Triggering receptor expressed on myeloid cells 2) gene, which encodes a protein expressed selectively by microglia in the brain, have been linked to disrupted binding of lipoproteins and are associated with the development of Alzheimer’s disease (AD). More...
03 Aug 2016
Image: A structural model of the RUNX3 protein (Photo courtesy of Wikimedia Commons).

Phosphorylation Turns a Tumor Suppressor into a Promoter of Cancer Development

Cancer researchers have determined the molecular mechanism by which a modification to the protein encoded by the RUNX3 gene turns a tumor suppressor into a promoter of cancer development and progression. More...
03 Aug 2016

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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