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Image: A new finding goes against dogma, showing for the first time that the building blocks of a protein, called amino acids, can be assembled by another protein, and without genetic instructions. The Rqc2 protein (yellow) binds tRNAs (dark blue, teal), which add amino acids (bright spot in middle) to a partially made protein (green). The complex binds the ribosome (white) (Photo courtesy of Janet Iwasa, PhD, University of Utah).

Challenging Classic Science Principles, New Research Finds New Role for Proteins

A new study revealed for the first time that the essential components of a protein, called amino acids, can be assembled without blueprints—DNA and an intermediate template called messenger RNA. Researchers have observed an instance in which another protein specifies which amino acids are added.   More...
14 Jan 2015
Image: Molecular structure of phosphatidylinositol (Photo courtesy of Wikimedia Commons).

Cancer Cells with p53 Mutations Have Phosphatidylinositol Signaling Molecules with Shortened Lipid Acyl Chains

A recent study showed that cancer cells with mutations in the p53 gene were distinguished by reduced-length fatty acid moieties in their cell membranes.  More...
13 Jan 2015

Enzyme Found to Trigger the Immune System, Providing Clues on Alzheimer’s-Related Protein

New findings with a specific enzyme could provide more clues on presenilin functions, in addition to providing a better determination into how the immune system is controlled.  More...
13 Jan 2015
Image: Micrograph showing human chromosomes (grey) capped by telomeres (white) (Photo courtesy of the US Department of Energy Human Genome Program).

Experimental Cancer Drug Disrupts Telomerase Function

Cancer researchers have published a detailed study of the potential chemotherapeutic drug 6-thio-2'-deoxyguanosine, a potent inhibitor of the enzyme telomerase.  More...
12 Jan 2015

Genome Editing Application Has Potential in Modifying Human Stem Cells

A unique genome editing tool known as CRISPR has been used by researchers for several years to fit, replace, disrupt, or add to sequences of an organism’s DNA. Now, scientists have shown that the system also precisely and effectively changes human stem cells, which could become a new advance in the use of stem cells for treatment and disease research.  More...
12 Jan 2015

Protein Bioengineering Applications May Offer a Treatment for Huntington’s Disease, Improving Motor Function and Reducing Brain Shrinkage

Researchers have improved motor function and brain abnormalities in lab animals with a form of Huntington’s disease, a severe neurodegenerative disorder, by modifying the levels of a key signaling protein. This new findings may become the basis of a new treatment for individuals suffering from this lethal, progressive disease.  More...
11 Jan 2015
Image: Color-coded image shows the surface view of enterovirus D68, which has stricken children with serious respiratory infections and might be associated with polio-like symptoms. Red regions are the highest peaks, and the lowest portions are blue. In the black-and-white background are actual electron microscopy images of the EV-D68 virus (Photo courtesy of Purdue University).

Study Suggests Pleconaril Has Potential to Treat EV-D68 Infection

The antiviral drug pleconaril effectively blocks the spread of laboratory strains of EV-D68 virus but fails to protect against the strains currently causing an outbreak of childhood respiratory disease in the United States.  More...
11 Jan 2015

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.


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