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Genomics/Proteomics

Image: Ball-and-stick model of the naphthalene molecule, as determined from X-ray crystallographic data (Photo courtesy of Wikimedia Commons).

Naphthalene-Dipeptide Hydrogels Destroy Antibiotic-Resistant Bacterial Biofilms

Novel hydrogels derived from self-assembling dipeptides conjugated to naphthalene were shown to dissolve bacterial biofilms, which indicated considerable promise for use in constructing bacteria-resistant nanomaterial structures, biomaterials, and drug delivery devices.  More...
03 Sep 2014
Image: Difference in DP103 (red) levels in a healthy person (left image) and a breast cancer patient (right image) (Photo courtesy of the National University of Singapore).

DP103 Cited as Breast Cancer Biomarker and Potential Treatment Target

Cancer researchers in Singapore have identified the DP103 oncogene in human breast cancers as a biomarker for the molecular processes that drive reappearance and metastasis of tumors following chemotherapy.  More...
02 Sep 2014
Image: A leukemia cell coated with antibody is marked for destruction by activated natural killer cells (Photo courtesy of the University of Southern California).

Leukemia Cells Are Killed in Culture by Immune Cells Grown from the Same Patient

Immune system natural killer cells were isolated from leukemia patients, expanded in culture, and then shown in an in vitro system to attack and destroy cancer cells from the original cell donors.  More...
01 Sep 2014
Image: Diagram illustrates the innovative process that could lead to more effective drugs against influenza infection (Photo courtesy of the Hebrew University of Jerusalem).

Researchers Show How the Influenza Virus Blocks Natural Killer Cell Recognition

A team of molecular virologists has described how the influenza virus evolved a defense mechanism to protect it from attack by the immune system's natural killer cells.  More...
31 Aug 2014

Genome-Wide Mutation-Searching Computational Software Designed for Genomic Medicine

Analysis software cross-references a patient’s symptoms with his genome sequence to help physicians in the diagnosis of disease.   More...
31 Aug 2014
Image: Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond. They are found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals (Photo courtesy of Wikimedia Commons).

Elevated Levels of IgG2 Antibodies Protect Some Types of Gram-Negative Bacteria

The finding that an overabundance of a certain class of antibodies protects some bacteria from the effects of antibiotics has marked implications for our understanding of the protection generated by natural infections and for the design of vaccines, which should avoid inducing such inhibitory antibodies.  More...
27 Aug 2014

Partnership Established to Decode Bowel Disease

23andMe, a personal genetics company, is collaborating with Pfizer, in which the companies will seek to enroll 10,000 people with inflammatory bowel disease in a research project designed to explore the genetic factors associated with the onset, progression, severity, and response to treatments for IBD.  More...
25 Aug 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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