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05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017
12 Apr 2017 - 14 Apr 2017

Genomics/Proteomics

Image: A photomicrograph of a nerve cell (the small orange-spotted cell on the far left) from a pigtailed macaque infected with herpes virus (Photo courtesy of the Seattle Children\'s Research Institute).

Novel Monkey Model to Enable Study of Dormant Herpes Infections

A team of molecular virologists has demonstrated the potential of the pigtailed macaque monkey model as a platform to study the implications of dormant herpes viruses on individuals with compromised immune systems. More...
01 Sep 2016
Image: Protective telomeres are augmented by freely diffusing telomerase (Photo courtesy of University of Colorado Cancer Center).

Single Molecule Imaging Reveals How Telomerase Finds and Binds to the Telomere

Genomics researchers have combined the CRISPR/Cas9 gene editing technique with advanced single-molecule imaging technology to demonstrate how the enzyme telomerase finds and attaches to the telomere, the region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. More...
31 Aug 2016
Image: The enzyme HtrA1 shown in the image degrades ApoE4, the strongest genetic risk factor for Alzheimer’s disease, providing new information that might eventually lead to new treatments for the neurodegenerative disorder (Photo courtesy of Salk Institute for Biological Studies).

Release of ApoE4 Fragments and Increased Tau Protein Contribute to Risk of Alzheimer's Disease

Results of a recent study suggested that the interaction between apolipoprotein E4 (ApoE4) and the enzyme high-temperature requirement serine peptidase A1 (HtrA1) was linked in some fashion to the development of late onset Alzheimer's disease (AD). More...
31 Aug 2016
Image: A colored transmission electron micrograph (TEM) of norovirus (Photo courtesy of  Charles D. Humphrey, CDC).

Researchers Identify Cell Surface Protein Required for Norovirus Infection

Molecular virologists working with a mouse norovirus strain identified and characterized a cell surface protein that was required by the virus to gain entry into the host cell. More...
31 Aug 2016
Image: The first 3D map of the cancer-associated protein DCLK1 (doublecortin-like kinase 1), revealed how it functions (Photo courtesy of Walter and Eliza Hall Institute).

Kinase Domain Mutation Causes Protein Malfunction and Tumor Development

A team of chemical biologists has generated the first molecular map of the protein doublecortin kinase like domain 1 (DCLK1), a factor linked to more than 10% of gastric cancers that has also been found in kidney, rectal, and pancreatic cancers. More...
29 Aug 2016
Image: The crystal structure of Cas9 bound to DNA (Photo courtesy of Wikimedia Commons).

Unrelated Single-Stranded DNA Increases Efficiency of CRISPR-Cas 9 Gene Editing

The addition of a short section of single-stranded DNA to the reaction mixture significantly enhances the efficiency of the CRISPR/Cas9 gene editing technique. More...
29 Aug 2016
Image: Healthy blood cells along with sickle-cell diseased cells (Photo courtesy of Science Picture Co./Corbis).

Gene Editing Corrects Hemoglobin Defects in Beta-Thalassemia and Sickle Cell Disease

A team of hematology researchers used the CRISPR/Cas9 gene editing technique to correct the mutations that cause defective blood cell morphology in beta-thalassemia and sickle cell disease. More...
25 Aug 2016


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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