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Genomics/Proteomics

Image: Dutch process cocoa (left) compared to natural cocoa (right) (Photo courtesy of Wikimedia Commons).

Polyphenol-Rich Cocoa Extracts Protect Against Alzheimer's Disease

A recent paper suggested that flavonol-rich cocoa extracts interfere with the processes that lead to the development of Alzheimer's disease.  More...
08 Jul 2014

Diabetes Linked to Faulty Mitochondria Disposal Pathway

A molecular pathway that regulates the disposal of defective mitochondria has been cited as a potential target for prevention and control of diabetes and certain other diseases.  More...
08 Jul 2014
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Image: A structural model of the beta2 adrenergic receptor-arrestin signaling complex as deduced by electron microscopy, cross-linking, and mass spectrometry (Photo courtesy of Duke University).

Advanced Electron Microscopy Reveals Fine Structure of Active Signaling Complexes

A team of molecular biologists used advanced electron microscopy and mass spectroscopy techniques to determine the structure of the functional human beta2AR-beta-arrestin-1 signaling complex.  More...
07 Jul 2014
Image: Osteoclast, with bone below it, shows typical distinguishing characteristics: a large cell with multiple nuclei and a “foamy” cytosol (Photo courtesy of Wikimedia Commons).

A MicroRNA Regulates the Mechanism That Prevents Osteoporosis and Bone Metastasis

A study conducted on a mouse model of osteoporosis found that animals with higher than normal levels of the microRNA miR-34a were protected from the syndrome by having increased bone mass and reduced bone breakdown.   More...
07 Jul 2014
Image: Space-filling model of the cholesterol molecule (Photo courtesy of Wikimedia Commons).

Cholesterol Inhibitor Blocks Breast Cancer Growth in Mouse Model

A low molecular weight drug that inhibits cholesterol biosynthesis was found to block the growth of breast tumors by modifying the ratio of proliferative and antiproliferative estrogen receptors.   More...
02 Jul 2014

Cholesterol Metabolite Contributes to Buildup of Atherosclerotic Plaques

A recent paper described the mechanism by which the cholesterol metabolite 27-hydroxycholesterol contributes to the development of the fatty plaques that characterize atherosclerosis.  More...
01 Jul 2014

Nanoscale Velcro Proteins Discovered to Be Used for Molecule Transport

Scientists have discovered that proteins found within the nuclear pore function similar to a “Velcro” snap that can be used for controlled and selective transport of particles.   More...
01 Jul 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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