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Genomics/Proteomics

Evolutionary Changes Reproduced in the Lab by Manipulating Embryonic Development of Mice

Researchers have been able experimentally to reproduce in mice morphologic alterations that have taken millions of years to occur.  More...
18 Aug 2014
Image: Molecular tags of DNA damage are highlighted in green in blood-forming stem cells (Photo courtesy of UCSF – University of California, San Francicsco).

DNA Replication Difficulty May Be Key to Immune System Aging

People over 60 are not donor candidates for bone marrow transplantation; the immune system ages and weakens with time, making the elderly predisposed to life-threatening infection and other disorders. US researchers have now have found a reason.  More...
13 Aug 2014

Imaging, Genetic Testing Reveal that Tyrolean Iceman had Genetic Predisposition for Atherosclerosis

Although prevalence and types of risk factors for atherosclerosis have varied over time from ancient times to modern society, genetic predisposition/risk for the disorder now appears to be very similar to that in ancient times, according to new imaging and genetic findings gleaned from a 300-year-old glacier mummy.  More...
13 Aug 2014
Image: Electron microscopy image of the bacteriophages investigated (Photo courtesy of the European Molecular Biology Laboratory).

Crystal Structures Define Mode of Action of Bacteriophage Endolysins

 New antibacterial agents based on bacteriophages or their endolysin enzymes have been proposed to solve the problem of the bacterium Clostridium difficile, which is becoming a serious health hazard in hospitals and healthcare institutes, due to its resistance to antibiotics. More...
13 Aug 2014

Factors in the Tumor Microenvironment Promote Cancer Growth and Metastasis

Cancer researchers have found that procancerous HSF1 drives a transcriptional program in cancer-associated fibroblasts that complements, yet is completely different from, the program it drives in adjacent cancer cells.  More...
13 Aug 2014

New Drug Shown to Be Effective Against Malaria Using Synchrotron Light

 Spanish and Scottish investigators have shown that a new drug is an effective option in the battle against malaria.  More...
04 Aug 2014
Image: This beta cell that has non-functioning autophagy shows increased oxidative damage (stained in red) in the pancreatic islets (shown in white) (Photo courtesy of UCLA - University of California, Los Angeles).

Defective Autophagy Triggers Type II Diabetes in Mouse Model

A defect in the cellular cleansing process known as autophagy in individuals with type II diabetes causes the build-up of toxic beta-cell amyloid polypeptide, a scenario similar to the build-up of beta amyloid peptides in Alzheimer's disease.  More...
04 Aug 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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