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Genomics/Proteomics

Large Genetic Study Identifies New Prostate Cancer Loci

Data obtained during a large genetic screening study have added 23 new genetic variants to the known loci linked to development of prostate cancer.  More...
21 Sep 2014
Image: Investigators identified individual unlabeled proteins by the weak shadow that the biomolecules produce when they scatter laser light (Photo courtesy of the Max Planck Institute for the Science of Light).

Laser Scattering Technique Detects Single Molecules

A recent paper described a novel technique for the label-free detection of single biomolecules such as tumor markers, proteins, or RNA fragments.  More...
21 Sep 2014
Image: Alternative splicing produces two protein isoforms (Photo courtesy of Wikimedia Commons).

Key Regulator of Cancer-Inducing Alternative Splicing Identified

Cancer researchers have identified the splicing factor RBM4 as a key determinant in processes that prevent tumor development and spread.  More...
17 Sep 2014
Image: Differences in the structure of a small lung artery (top row) and heart cross section (lower row) of rodents without disease (far left column); with pulmonary hypertension (middle) and a diseased rodent treated with the HDL peptide (right). Note the much narrowed lung artery, and thick walls and larger chamber of the heart in the diseased animal and improvements with 4F peptide treatment (Photo courtesy of UCLA - University of California, Los Angeles).

Apolipoprotein A-1 Mimetic Peptide Reverses Pulmonary Hypertension in Rodent Models

A small peptide that mimics the activity of apolipoprotein A-1, the main protein component of the high density lipoproteins, counteracted the effects of oxidized lipids and alleviated symptoms of pulmonary arterial hypertension in a population of laboratory animals.   More...
14 Sep 2014

Important Immune Cell Regulators’ Response Identified

A new strategy could help accelerate laboratory research and the development of potential therapeutics, including vaccines. The technology may also be used to identify the genes that underlie tumor cell development.   More...
14 Sep 2014

Synthetic Virus Designed to Enhance Delivery of New Generation of Pharmaceutical Agents

Dutch scientists have effectively developed an artificial virus that may be used for the delivery of a new generation of pharmaceutical agents, consisting of large biomolecules, by packaging them in a natural manner and delivering them to diseased cells.   More...
10 Sep 2014

DNA Amplification Kit Enables Investigation of the Genome from a Single Cell

A newly released DNA amplification kit enables biotech and other life science researchers to accurately and reproducibly amplify and investigate genomic DNA from single cells.  More...
09 Sep 2014


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
 
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