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Image: Biopsy of small bowel showing celiac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts (Photo courtesy of Wikimedia Commons).

Reduced Elafin Levels Associated with Celiac Disease Bowel Inflammation

Levels of the enzyme elafin, an endogenous serine protease inhibitor, were lower in the small intestinal epithelium of patients with active celiac disease as compared to similar tissue from control patients.   More...
22 Apr 2014

A Pair of Gene Splice Isoforms Has Opposite Effects on Cancer Development

Two distinct splice isoforms of the MAP kinase interacting serine/threonine kinase 2 gene have dramatically different roles in cancer development and growth.  More...
21 Apr 2014

Microarray Gene Expression Approach May Help Predict Cancer Patient Survival

A new predictive genetic tool is being developed that could help cancer patients and their physicians decide whether follow-up treatments are likely to help.  More...
14 Apr 2014
Image: The TheraCyte cell encapsulation device (Photo courtesy of TheraCyte, Inc.).

Encapsulated Human-Insulin-Producing Progenitor Cells Cure Diabetes in Mouse Model

A breakthrough system that allows subcutaneous implantation of encapsulated immature pancreatic cells was shown to produce enough insulin to correct the symptoms of diabetes in a mouse model.  More...
08 Apr 2014

Big Data’s Direct Coupling Analysis Reveals Clues About Molecular Protease Machines

Researchers have merged genetic and structural data in a Big Data attempt to solve one of the most fascinating mysteries in biology: how proteins perform the regulatory processes in cells upon which all life depends.  More...
07 Apr 2014

Chitosan Treatment Clears the Way for Antibiotics to Eliminate Recurrent Urinary Tract Infections

Recurrent urinary tract infection was successfully resolved in a mouse model by treatment with the exfoliant chitosan followed by a round of antibiotics.  More...
06 Apr 2014

Transforming Methylated Nucleic Acids into Prostate Tumor Biomarkers

High quality oligonucleoside reagents and detection kits are facilitating research on methylated DNA and its relation to the molecular mechanisms that drive development of prostate cancer.  More...
06 Apr 2014

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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