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Events

05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017
12 Apr 2017 - 14 Apr 2017

Genomics/Proteomics

Image: A laboratory-generated melanoma tumor (Photo courtesy of Dr. Aaron Smith, Queensland University of Technology).

Cancer Researchers Identify Factors That Drive Melanoma Metastasis

Cancer researchers have traced a molecular pathway that cycles melanoma cells between modes that favor growth of the primary tumor (progression) and modes that favor invasion of other parts of the body (metastasis). More...
23 Feb 2017
Image: Induced pluripotent stem cells (iPSCs) are the basis of a technique that opens the doors to many medical advances involving repair and restoration of tissues and organs (Photo courtesy of Darryl Leja, National Human Genome Research Institute).

Stem Cell Therapy is Safe: Reprogramming Does Not Increase the Rate of Mutagenesis

DNA mapping studies have shown that the genomes of induced pluripotent stem cells do not contain more mutations that did the original cell line from which they were generated. More...
22 Feb 2017
Image: A close-up image of a microfluidic chip used to fabricate nanoparticles that could be used to deliver therapeutic genes to specific organs of the body. Colored liquids have been added to highlight the channels (Photo courtesy of Rob Felt, Georgia Institute of Technology).

DNA Labels Simplify Development of Drug Delivery Nanoparticles

A team of biomedical engineers developed a method for labeling potential drug delivery nanoparticles with DNA "barcodes," which allowed the tracing of the nanoparticles within living test animals. More...
21 Feb 2017
Image: A photomicrograph of keratin filaments inside cells (Photo courtesy of Wikimedia Commons).

Enzyme Responsible for Skin Thickening Disorder Linked to Esophageal Cancer

A recent paper explained the molecular mechanism underlying the development of palmoplantar keratoderma (thickening of the skin on the palms of the hands and soles of the feet) in the rare genetic disease Tylosis with esophageal cancer (TOC). More...
17 Feb 2017
Image: Dopamine-making cells in a mouse brain (Photo courtesy of Sung-ung Kang, Johns Hopkins University).

Defects in Newly Identified Molecular Pathway Lead to Parkinson's Disease

A molecular pathway has been traced that protects dopamine producing neurons and prevents Parkinson's disease, and this finding may pave the way for development of drugs to correct defects in this pathway in individuals who have the disease. More...
16 Feb 2017
Image: A ball and stick model of creatine (Photo courtesy of Wikimedia Commons).

Defects in Creatine Metabolism Linked to Inflammatory Bowel Diseases

A mutation in the gene that encodes the enzyme glycine amidinotransferase has been linked to the development of inflammatory bowel diseases (IBDs) such as ulcerative colitis and Crohn's disease. More...
15 Feb 2017
Image: An adult heart muscle cell, grown in a newborn rat heart (Photo courtesy of Chulan Kwon, Johns Hopkins University School of Medicine).

Mature Heart Muscle Cells Created from Implanted Stem Cells

Bypassing a longstanding tissue culture challenge, researchers have succeeded in generating mature and viable human heart muscle cells in the laboratory by implanting, into newborn rat hearts, induced pluripotent stem cells (I-PSCs) from a healthy adult or an adult with a type of heart disease. The host rat heart provides the signals and chemistry needed by the implanted human immature heart muscle cells to progress and overcome the developmental block that has otherwise prevented their maturation in lab cultures. More...
10 Feb 2017


BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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