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05 Mar 2017 - 09 Mar 2017
20 Mar 2017 - 23 Mar 2017
12 Apr 2017 - 14 Apr 2017


Image: A scanning electron microscopic (SEM) image of a single human lymphocyte (Photo courtesy of Wikimedia Commons).

MicroRNAs Play a Critical Role in B Cell Maturation

A recent paper highlighted the important role of microRNAs in the maturation of the immune system's B lymphocytes (B cells). More...
07 Dec 2016
Image: A C10 antibody (purple) interacting with the Zika virus coat (green) (Photo courtesy of Victor Kostyuchenko, Duke-NUS Medical School).

Antibody-Zika Virus Interaction Visualized by Cryo-Electron Microscopy

An international team of molecular virologists used advanced cryo-electron microscopy (cryoEM) techniques to visualize how the potent anti-Zika virus antibody C10 acts to prevent the virus from infecting human cells. More...
07 Dec 2016
Image: A representation of the different cell types in the rheumatoid synovium (Photo courtesy of the University of Birmingham).

Two Classes of Fibroblasts Inhabit the Synovial Membrane in RA

Rheumatoid arthritis researchers have identified two distinct classes of synovial fibroblasts (SFs) differentiated by expression of either PDPN (podoplanin) or CD248 (endosialin), which were located within different anatomical compartments of the inflamed synovial membrane. More...
07 Dec 2016
Image: A photomicrograph of a mouse macrophage of extending pseudopodia to engulf two particles, possibly pathogens (Photo courtesy of Wikimedia Commons).

HDL Increases Macrophage Immune Response

While high-density lipoproteins (HDL) protect against atherosclerosis by inhibiting inflammation in the endothelial and smooth muscle cells that comprise the arterial wall, in immune macrophages HDL instead increases the inflammatory response. More...
01 Dec 2016
Image: The neuromuscular junction is the synapse where motor neurons communicate with muscle to initiate voluntary movement. A healthy neuromuscular junction (yellow) is characterized by perfect apposition between the motor neuron (green) and nicotinic acetylcholine receptors on the muscle (red). This synapse is damaged early in ALS, a change believed to contribute the onset and progression of the disease (Photo courtesy of the Virginia Tech Carilion Research Institute).

Faulty Protein Interaction Disrupts Neuromuscular Junctions and Triggers ALS

Humans and mice are protected from developing amyotrophic lateral sclerosis (ALS) by the action of muscle fibers that secrete and concentrate the fibroblast growth factor binding protein 1 (FGFBP1) at neuromuscular junctions. More...
01 Dec 2016
Image: A micrograph of cells in the thymus, an organ located just above the heart that trains immune T-cells to defend the body against viruses and bacteria (Photo courtesy of the Walter and Eliza Hall Institute).

Study Explains How Protein Complex Mediates T-cell Development

A recent paper extended our understanding of how T-cells develop into critical components of the immune system that are able to fight off pathogens without going out of control and triggering an autoimmune response. More...
30 Nov 2016
Image: Two fluorescent microscopy images of intestinal organoids growing in synthetic hydrogels (Photo courtesy of N. Gjorevski, Ecole Polytechnique Fédérale de Lausanne).

Synthetic Hydrogel System for Growth of Intestinal Organoids

A process for using artificial hydrogel matrices to grow miniature organs (organoids) derived from stem cell precursors was described in a recent paper. More...
30 Nov 2016

BioResearch's Genomics/Proteomics channel brings the latest research news on the proteome, the epigenome, metabolomics, their tools and methods.
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